Protein Info for ABZR87_RS01520 in Ralstonia sp. UNC404CL21Col
Annotation: IlvD/Edd family dehydratase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 87% identical to ARADA_AZOBR: L-arabonate dehydratase (araC) from Azospirillum brasilense
KEGG orthology group: K13875, L-arabonate dehydrase [EC: 4.2.1.25] (inferred from 99% identity to rpi:Rpic_3005)Predicted SEED Role
"L-arabonate dehydratase (EC 4.2.1.25)" in subsystem L-Arabinose utilization (EC 4.2.1.25)
MetaCyc Pathways
- L-arabinose degradation III (5/6 steps found)
- L-arabinose degradation IV (6/8 steps found)
- L-arabinose degradation V (4/6 steps found)
- superpathway of pentose and pentitol degradation (17/42 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 4.2.1.25
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (578 amino acids)
>ABZR87_RS01520 IlvD/Edd family dehydratase (Ralstonia sp. UNC404CL21Col) MSESKPKLRSAQWFGTADKNGFMYRSWMKNQGIPDHEFDGRPIIGICNTWSELTPCNAHF RKLAEHVKRGIYEAGGFPVEFPVFSNGESNLRPTAMLTRNLAAMDVEEAIRGNPIDAVVL LTGCDKTTPALLMGAASCDVPAIVVTGGPMLNGKLDGKNIGSGTAVWQLHESLKAGEIDL HHFLSAEAGMSRSAGTCNTMGTASTMACMAEALGTSLPHNAAIPAVDARRYVLAHMSGIR IVEMALQGLTLSKILTRAAFENAIRVNAAIGGSTNAVIHLKAIAGRIGVPLELEDWSRIG RDTPTIVDLMPSGRFLMEEFYYAGGLPAVLRRLGEAKLLPHPDALTVNGKTLWENVKSAP ITDDEVIRPLTNPLIDDGGIRVLRGNLAPRGAVLKPSAASPELLRHRGRAVVFENLEHYK ERIVDETLEVDASSVLVMKNCGPKGYPGMAEVGNMGLPPKLLRQGVKDMVRISDARMSGT AYGTVVLHVAPEAAAGGPLAAVQDGDWIELDCEAGTLHLDIDDAELARRMAAYQAPRSHG EGGGYQRLYVNHVLQADEGCDLDFLVGCRGAAVPRHSH