Protein Info for ABZR87_RS00815 in Ralstonia sp. UNC404CL21Col

Annotation: acylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 794 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF01804: Penicil_amidase" amino acids 41 to 782 (742 residues), 436.7 bits, see alignment E=1.2e-134

Best Hits

KEGG orthology group: K07116, (no description) (inferred from 96% identity to rpf:Rpic12D_2419)

MetaCyc: 85% identical to acyl-homoserine lactone acylase precursor (Ralstonia sp. XJ12B)

Predicted SEED Role

"penicillin amidase family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (794 amino acids)

>ABZR87_RS00815 acylase (Ralstonia sp. UNC404CL21Col)
MQRFMQGFARGALATAALAALAGCASTDSGWATPSDTGLSADISRTRFGIPHVRANDYAS
LGFGMAYAYAQDNVCLLADQVVTVNGERSKTFGPDGTVVVSFKPVPNTQADAFFKGAFDE
AGLRAGYAQMSPEARELLRGYIVGYNRYLKDTPPASRPAACRNADWVRPLTVADMMLMGE
EKAIQASAGAMLQSIVAAQPPGGAPASAVIPPHAVDTAALDRDLQLRDMPIGSNGWAFGK
TATDTGRGVLLGNPHFPWTTTNRFYQVHLTVPGKLDVMGASIAAFPVVSIGFNKDVAWTH
TVSTGRRFTLFELKLAEGDPTTYLIDGKPHKMTTRTVAFDVKLPDGRIERRTHTFYNTVY
GPVLSMPAGGMPWTSQKAYTLRDVNRNNTRSIDTWLHIAQAKDVAGIRQAIGNLGIPWVN
TIATDRNGRALFADVSTTPDVSTEALKRCAPSPLADKLFKGVGLVLLDGSRSACNWQIDP
ASPVPGLVAPARMPVLERDDYVANSNDSSWLTNPAQKLMGFSPVMGSTDVPQRLRTRIGI
IEIERRLAGTDGLPGNKVNLPNLQSMIFRNANLAGHLVRDDLLTACKATANLDADVRDGC
AALAQWNLTDNVDARAAHVFREFWMRAKDIPNVYAVDFNPADPVYTPHSLRMSDPTVRAA
VFKALKDAVGAVRTAGFALDAPLGAVQAAHAPGGDIALHGGEEYEGVLNKLQSTPIGPKG
LQVYFGTSYIQTVTFDDQGPVADALLTYGESTDPASPHAFDQMREFSAKRWNRLPFSEAA
IAADPALKVTKLSQ