Protein Info for ABZR87_RS00665 in Ralstonia sp. UNC404CL21Col
Annotation: amino acid ABC transporter ATP-binding protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 56% identical to GLNQ_GEOSE: Glutamine transport ATP-binding protein GlnQ (glnQ) from Geobacillus stearothermophilus
KEGG orthology group: K02028, polar amino acid transport system ATP-binding protein [EC: 3.6.3.21] (inferred from 98% identity to rpi:Rpic_2796)MetaCyc: 56% identical to cystine ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-290 [EC: 7.4.2.12]; 7.4.2.12 [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]
Predicted SEED Role
"Cell division transporter, ATP-binding protein FtsE (TC 3.A.5.1.1)" in subsystem Bacterial Cell Division (TC 3.A.5.1.1)
Isozymes
Compare fitness of predicted isozymes for: 3.6.3.21
Use Curated BLAST to search for 3.6.3.21 or 7.4.2.12
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (266 amino acids)
>ABZR87_RS00665 amino acid ABC transporter ATP-binding protein (Ralstonia sp. UNC404CL21Col) MNMTNANLQTLKSALDVPMIQIRGLTKSYGDHTVLKGIDFDVDASQVVVVIGPSGSGKST FLRCCNGLETAEGGTIDICGNRLIDNGKLLPDGELNQLRQQVGMVFQSFNLFPHLSVLHN VTVGPRMLSGKSKHEAETEARELLQKVGLAHKADAMPASLSGGQKQRVAIARALAMRPKV MLFDEPTSALDPELVGEVLQVMKLLAKEGMTMLVVTHEMGFAREVADVVVVMDGGGIVEA GPPSVIFGEPKEARTRSFLQAVLTRA