Protein Info for ABZR86_RS22105 in Dyella japonica UNC79MFTsu3.2

Annotation: protease pro-enzyme activation domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 875 signal peptide" amino acids 1 to 36 (36 residues), see Phobius details PF09286: Pro-kuma_activ" amino acids 82 to 216 (135 residues), 124.8 bits, see alignment E=4.8e-40 PF00801: PKD" amino acids 634 to 700 (67 residues), 39.7 bits, see alignment 5.3e-14 PF18911: PKD_4" amino acids 640 to 710 (71 residues), 55.7 bits, see alignment E=6.4e-19

Best Hits

Swiss-Prot: 59% identical to XANP_XANS2: Xanthomonalisin from Xanthomonas sp. (strain T-22)

Predicted SEED Role

"Xanthomonapepsin precursor (EC 3.4.21.101)" (EC 3.4.21.101)

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.101

Use Curated BLAST to search for 3.4.21.101

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2JNS4 at UniProt or InterPro

Protein Sequence (875 amino acids)

>ABZR86_RS22105 protease pro-enzyme activation domain-containing protein (Dyella japonica UNC79MFTsu3.2)
MSSQKYSWGITNKLYRKALLPAAVSMAMLAGSAQAADNWVGTKTHPAIEKSGAGVSTLST
ANTGAQWTIRMRGNPTVDNALVTPLEQSKPLHVAVSLKLRNADQLQQFLHELATPGSAHY
GKYLTPAQFKAAYAPTEQQVQAVVAHLRAAGFDNVTVSPNNLLVEADGNAGHVQAAFRTT
MKTFQFRGRQRVANDGEVQVPASLADTVDAVLGLQDVSVKHTMHHVLKQLTPAEIHPNAT
TATVASHNPKDFPAIYDVGSVPAATNTTVGIVTWGATTTTINDLNTFTSNAGLPTTNVQT
VKVGTAALWDDTDGDGEWNLDSQTIVGTTGGVQKLIFYTAANGTNNASLTDAGITAAYNK
AVTDNVAKVVNVSLGEDETAAHNAGTQQADDNVFQQAVAQGQTFSISSGDEGVYESQGGV
LTNSSGTVTADLTAYSVSEPAASPYVVAVGGTTLSTNGTTWAGETVWNEGLATVSSTDTR
KRLWATGGGVSSFETAPSWQTAALGSSVTKRVLPDVAFDAAQSSGAQIVYQGGTYAIGGT
SLASPIFVGVWARLQSNNGNALPFPTSKFYGDFPNHPELLHDVTSGNNGYSGHGYNAAAG
WDYTTGFGSLDISKVNAFAAANWVSGGSTGGTPTANFSFTTSGLTANFTDSSTDSGGTIS
SHAWTFGDGGTSTATSPSHTYAAAGTYTVTETVTDGTSGKTSAKSSSVTVSSGGGGATQL
LGNPGFETGTASPWSISSGALCSNSSCSGQTAHGGTWFTWLDGYGSSHTDTVSQSVAIPA
GKTSASLTFYLHIDTAETTTSTAYDKLNVQVLNSSGTVLKTLATYSNLNKASGYALKTFD
LSAYIGQTVTIKFTGTEDSSQQTSFVLDDVNLNVQ