Protein Info for ABZR86_RS21965 in Dyella japonica UNC79MFTsu3.2

Annotation: transcription termination/antitermination protein NusG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 186 PF02357: NusG" amino acids 3 to 116 (114 residues), 98 bits, see alignment E=3.7e-32 TIGR00922: transcription termination/antitermination factor NusG" amino acids 5 to 185 (181 residues), 208.1 bits, see alignment E=4.1e-66 PF00467: KOW" amino acids 135 to 165 (31 residues), 30.4 bits, see alignment 2.4e-11

Best Hits

Swiss-Prot: 77% identical to NUSG_XYLFA: Transcription termination/antitermination protein NusG (nusG) from Xylella fastidiosa (strain 9a5c)

KEGG orthology group: K02601, transcriptional antiterminator NusG (inferred from 85% identity to xal:XALc_0502)

Predicted SEED Role

"Transcription antitermination protein NusG" in subsystem Transcription factors bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2K2A7 at UniProt or InterPro

Protein Sequence (186 amino acids)

>ABZR86_RS21965 transcription termination/antitermination protein NusG (Dyella japonica UNC79MFTsu3.2)
MSKRWYVVHAYSGFENQVRKSLVERIQRAGMEERFGEVLVPTEEVIEMRGGQKRRSDRKF
FPGYVLVQIETDTEGKAPRIDDECWHLVKETPKVMGFIGGTADRPLPIRDSEADNILSRV
REGVEKPKPKVLFEPGEMVRVTDGPFNDFNGVVEEVNYEKSRLRVAVLIFGRSTPVELEF
GQVEKA