Protein Info for ABZR86_RS21665 in Dyella japonica UNC79MFTsu3.2

Annotation: DNA polymerase III subunit alpha

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1189 TIGR00594: DNA polymerase III, alpha subunit" amino acids 5 to 1050 (1046 residues), 1243.1 bits, see alignment E=0 PF02811: PHP" amino acids 7 to 170 (164 residues), 131.2 bits, see alignment E=1.5e-41 PF07733: DNA_pol3_alpha" amino acids 290 to 566 (277 residues), 332.5 bits, see alignment E=6.3e-103 PF17657: DNA_pol3_finger" amino acids 569 to 735 (167 residues), 221.7 bits, see alignment E=1.1e-69 PF14579: HHH_6" amino acids 809 to 898 (90 residues), 105.1 bits, see alignment 5.5e-34 PF01336: tRNA_anti-codon" amino acids 1017 to 1088 (72 residues), 42.5 bits, see alignment 1.5e-14

Best Hits

Predicted SEED Role

"DNA polymerase III alpha subunit (EC 2.7.7.7)" in subsystem DNA-replication (EC 2.7.7.7)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2IZW0 at UniProt or InterPro

Protein Sequence (1189 amino acids)

>ABZR86_RS21665 DNA polymerase III subunit alpha (Dyella japonica UNC79MFTsu3.2)
MTVRFAHLHLHSEYSLVDSTIRIKALVDACVREGIPAVALTDETNMFALVKFYKACSAAG
IKPIGGCDLWLSMPDDPRPSRVTLICQNRDGYLNLSRLVSRVWREGQGSGKPMADAAWLT
PSATEGLIALVGRENEVARLAVNQGVAAAAARLRPFARLFQDRLYLELTRCGREGEETWN
AAALALAAELDLPVIASNDVRFLRQDDFESHEARVCIHQGRVLADPKRPRDYSDQQYLKT
PTQMAELFADIPEALENTVELAKRCTLELNFGTYYLPNFPVPEGHDLASYIRELSHEGLK
ERLASNPLAPGYTLEDYVARLDRELDVIIEMGFPGYFLIVADFINWGKQNGIPVGPGRGS
GAGSLVAWVLKITDLDPLPFNLLFERFLNPERVSMPDFDIDFCMDRRDEVIDYVARKYGR
DHVSQIITYGSMAAKAVLRDSGRVLGMGYNAVDKIAKLIPARPLDLTLSCALGRSEKAKK
EPDRVVKEFCDLYDQDEEAKTLIDLALSLENLTRNAGKHAGGVVIGPKPLTEFAPLYCEA
GGGGVVTQYDKDDVEAVGLVKFDFLGLRTLTIIDWAVKAINARRAASGEEPLDIAALPLD
DAATYKLLQQARTVAVFQLESSGMQRMLKDARADRFEDIVALVALYRPGPMDLIPSFVAR
KHGREEVQYPDPRVEPILKETYGIMVYQEQVMQMAQIVGGYSLGGADLLRRAMGKKKLEE
MAKERAKFREGAAKDGLSGEKADEIFDLMEKFAGYGFNKSHAAAYALVSYQTAWLKAHYP
AEFMAATISSDMDNTDKAVTFIDESKAIGLTVLPPDVNASEFMFVAVEPKVIRYGLGAIK
GVGQGACESIAEERERGGPYKDLADFCRRVDSTKLNRRVLEALILSGALDALAPTRASLM
LQLPDAIKAAEQHLRDKQSGQNDMFGAAMSDKSGGTVAPVVQIDLPTAPEWPLEQKLQGE
RDTLGHYLSGHPTDPWREELQQLSTCPLGEIADRYQPPRPRKGDDDNRFRRGPDTPWTVA
GMVTAIRKRGESDAFVRLEDGTGIIEVSFFGELYQQVAPLLTRDEILVVEGGLRIDDFSG
GGFAVRARSAHTLADACRRFARVLHVKLNGVGPGFVDQLRQILAGYRNGRTSVVLHGYHN
AIAQADLELGDAWRVEAIPELLRAVRAVPGVQAARLRIVKTDDRPSRGD