Protein Info for ABZR86_RS21210 in Dyella japonica UNC79MFTsu3.2

Annotation: transcription-repair coupling factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1152 PF17757: UvrB_inter" amino acids 130 to 219 (90 residues), 95.4 bits, see alignment 6.5e-31 TIGR00580: transcription-repair coupling factor" amino acids 148 to 1082 (935 residues), 1100.9 bits, see alignment E=0 PF21132: MFD_D3" amino acids 375 to 452 (78 residues), 72.5 bits, see alignment 7.7e-24 PF02559: CarD_TRCF_RID" amino acids 481 to 536 (56 residues), 65.7 bits, see alignment 1.1e-21 PF04851: ResIII" amino acids 605 to 762 (158 residues), 37.9 bits, see alignment E=6.3e-13 PF00270: DEAD" amino acids 606 to 768 (163 residues), 90.2 bits, see alignment E=4.5e-29 PF00271: Helicase_C" amino acids 806 to 910 (105 residues), 69.9 bits, see alignment E=7.8e-23 PF03461: TRCF" amino acids 1010 to 1102 (93 residues), 97.8 bits, see alignment E=1.4e-31

Best Hits

KEGG orthology group: K03723, transcription-repair coupling factor (superfamily II helicase) [EC: 3.6.4.-] (inferred from 51% identity to acd:AOLE_10625)

Predicted SEED Role

"Transcription-repair coupling factor" in subsystem DNA-replication or Transcription factors bacterial

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.-

Use Curated BLAST to search for 3.6.4.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2BKW5 at UniProt or InterPro

Protein Sequence (1152 amino acids)

>ABZR86_RS21210 transcription-repair coupling factor (Dyella japonica UNC79MFTsu3.2)
MPSPIPFPPLPTTPKHRRYWTPPHGSARALLVAETARAHAGLLVAVTRDTQRAHALEDEL
RLFAGDLPVLHFPDWETLPYDIFSPHPEIVSQRIATLYSLPSTRRGVLVVPVATLMQRIA
PHSHVTGSGLVLKKGQKLDLSTEQRRLEAAGYRNVPQVAEPGDFAVRGALIDIYPMGAGE
PYRIELFDDEVESIRSFDPETQRSQQPVEKVELLPAREFPLTEQAAKDFRGKLRERFPID
VRRCPLYQDMKEGVTPGGIEYYLPLFFEQTATLFDYLGDGAVFLLGEGTLESAEQFWQQT
GERYDQRAHDIERPVLPPAELYLPPEQLREQLNRRLRVEVVASGHEHAADVGTQPAPELP
LNRKGEEPGTSLRHFLASYPGRVLIAADSAGRREALIETLAAAGLKPDSIDGWPRFLAAD
GAGPKFAIAIAGLEQGFALKSPAITVLTERELYGERVRTERKRRRGAARDPDAIIRDLTE
LTIGAPIVHVDHGVGRYQGLVSMELGGTEGEFLTIEYAKGDKLYVPVAQLGLVSRYTGTA
PELAPLHSLGGDAWERARRKAAEKVRDVAAELLAIYAQREARGGQSLPIDRQLVEEFGAT
FPFEETPDQAQAIDAVLGDLAAPRAMDRVICGDVGFGKTEVALRAAFAAATAGKQVAVLV
PTTLLAQQHFRNFADRFADWPVRVDVLSRFKSSKEVNEALKRLADGQIDVIVGTHKLLQP
DIRFKDLGLVIVDEEQRFGVRQKEQLKKLRAEVDLLTMTATPIPRTLNMAMSGLRDLSLI
ATPPAHRMAVRTFVNAWDPATVREAFQRELARGGQVYFLHNEVESIERTARELQELIPEA
RIGIAHGQMAERELEQVMADFHRQRFNVLVCTTIIETGIDIPTANTIIIDRADRFGLAQL
HQLRGRVGRSHHRAYAYLIVPDRKAMTADAEKRLEALASLEELGAGFTLATHDLEIRGAG
ELLGDEQSGQIQEIGFGLYTELLERAVRALKSGKVPDFDLSSEHETEVELHLPALIPDDY
LPDVHTRLTLYKRIASARHDEALRDLQVEMIDRFGLLPEPTKTLFAIAGLKLMATPLGIR
KLDFGPNGGRITFRDKPEVDPMAIIRLIQGQPRVYKLDGQDKLKVLLELPGAAERIRTAQ
EILVQLGARRPA