Protein Info for ABZR86_RS20640 in Dyella japonica UNC79MFTsu3.2

Annotation: translational GTPase TypA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 609 PF00009: GTP_EFTU" amino acids 5 to 196 (192 residues), 188.8 bits, see alignment E=1.9e-59 TIGR00231: small GTP-binding protein domain" amino acids 6 to 156 (151 residues), 88.1 bits, see alignment E=5.7e-29 TIGR01394: GTP-binding protein TypA/BipA" amino acids 6 to 604 (599 residues), 917.6 bits, see alignment E=2.8e-280 PF01926: MMR_HSR1" amino acids 9 to 130 (122 residues), 23.8 bits, see alignment E=1.1e-08 PF03144: GTP_EFTU_D2" amino acids 220 to 290 (71 residues), 47.6 bits, see alignment E=4.6e-16 PF00679: EFG_C" amino acids 401 to 481 (81 residues), 73.9 bits, see alignment E=2.2e-24 PF21018: BipA_C" amino acids 490 to 598 (109 residues), 143.5 bits, see alignment E=5.1e-46

Best Hits

Swiss-Prot: 68% identical to TYPA_ECOLI: GTP-binding protein TypA/BipA (typA) from Escherichia coli (strain K12)

KEGG orthology group: K06207, GTP-binding protein (inferred from 90% identity to smt:Smal_0788)

Predicted SEED Role

"GTP-binding protein TypA/BipA" in subsystem Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2BYA1 at UniProt or InterPro

Protein Sequence (609 amino acids)

>ABZR86_RS20640 translational GTPase TypA (Dyella japonica UNC79MFTsu3.2)
MSIENLRNIAIVAHVDHGKTTLVDQLLKQSGTLSERTVLAERVMDSNDQEKERGITILAK
NTAITWQGNRINIVDTPGHADFGGEVERVLSMVDTVLILVDAMDGPMPQTRFVTQKAFAM
GFKPIVVVNKIDRPGSRPDWVVEQVWDLFDRLGATPEQMDFPIVYASALNGYASLDADTR
EGDMTPLYEAIMKHAPKPEVDPEGPFQMRISQLDYNNFVGVIGIGRIQRGTLKKNMPVAV
IDRHGKKRQGKILQVLGFMGLERIEQDTAEAGDIVAISGIQELTISDTVCALDTPEALPA
LTVDEPTISMTFQVNNSPFAGNKDLSGGKFLTSRQIKERLEREQVHNVALRVEQGSDADK
FLVSGRGELHLSVLIENMRREGYELAVSRPEVIIKEIDGQKMEPIEQLVVDVEEIHQGPV
MERLGIRKGALKNMEPDGKGRVRLEYMIPARGLIGFQNQFKTLTQGSGLLFHVFDHYGPK
EEGQIAKRLNGVMIANAAGNTPAYSLGPLQERGKLFAAEGDSVYEGQLVGIHAKDNDLTV
NAIKPKPLTNMRASGKDDAIQLTPAIKFSLEQALDFIDDDELVEITPKEIRLRKKHLTEN
DRKRASRGG