Protein Info for ABZR86_RS20510 in Dyella japonica UNC79MFTsu3.2

Annotation: amino acid permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 474 transmembrane" amino acids 32 to 55 (24 residues), see Phobius details amino acids 63 to 89 (27 residues), see Phobius details amino acids 95 to 112 (18 residues), see Phobius details amino acids 119 to 138 (20 residues), see Phobius details amino acids 159 to 178 (20 residues), see Phobius details amino acids 189 to 208 (20 residues), see Phobius details amino acids 220 to 239 (20 residues), see Phobius details amino acids 260 to 284 (25 residues), see Phobius details amino acids 304 to 327 (24 residues), see Phobius details amino acids 358 to 375 (18 residues), see Phobius details amino acids 381 to 402 (22 residues), see Phobius details amino acids 414 to 432 (19 residues), see Phobius details amino acids 438 to 456 (19 residues), see Phobius details PF13520: AA_permease_2" amino acids 30 to 452 (423 residues), 172.4 bits, see alignment E=2.4e-54 PF00324: AA_permease" amino acids 35 to 426 (392 residues), 145.4 bits, see alignment E=3.4e-46 PF13906: AA_permease_C" amino acids 411 to 461 (51 residues), 50.7 bits, see alignment 2.3e-17

Best Hits

Swiss-Prot: 47% identical to MTRTR_BACSU: Methylthioribose transporter (mtrA) from Bacillus subtilis (strain 168)

KEGG orthology group: K03294, basic amino acid/polyamine antiporter, APA family (inferred from 58% identity to rxy:Rxyl_2924)

Predicted SEED Role

"amino acid transporter protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2C3M5 at UniProt or InterPro

Protein Sequence (474 amino acids)

>ABZR86_RS20510 amino acid permease (Dyella japonica UNC79MFTsu3.2)
MGLIDDITRRKPVESLQREADTGTGLRRVLGLWQLTAIGLGGIIGVGIFVLTGTVAATQA
GPAVLLSFLLAGIASAAAALCYAEFAGLIPVSGSAYTYGYAVLGEFAGWIIGWDLLLEYA
LIAAVVAVGWSGYAQVLLDNFGLPLPTWAQGAWGTAPGRVVNLPAILISVLITALLAVRM
EWGARFNTLIVAIKIAGAALIVIAGAAYVKPERWHPFMPFGMHGVVTGAAVVFFAVFGYD
MLTTAAEESRNPQRDLPRAVLLSLGIAMLLYFAICLVLTGIVPYTTLDNDAPVANAFIRI
GMPWTMAVISLASVCGITSVIFANLLAGARIGFSLGRDGLLPGWFAGIHPRWRTPHRATF
LLGTVTAVASGLFPLDELAKLVNIGVLGAFIVICTAVAVLRWRRPELHRPFRTPWVPFVP
LVGVGFSCWLIWGVPAVTYVRFGIWLLVGCVVYLGYGRSHSRLAARGLAAAARK