Protein Info for ABZR86_RS20500 in Dyella japonica UNC79MFTsu3.2

Annotation: Xaa-Pro peptidase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 401 PF01321: Creatinase_N" amino acids 36 to 168 (133 residues), 76.7 bits, see alignment E=2.5e-25 PF00557: Peptidase_M24" amino acids 176 to 383 (208 residues), 193.6 bits, see alignment E=3.8e-61

Best Hits

KEGG orthology group: K01271, Xaa-Pro dipeptidase [EC: 3.4.13.9] (inferred from 71% identity to xcb:XC_1703)

Predicted SEED Role

"Predicted 4-hydroxyproline dipeptidase" in subsystem Proline, 4-hydroxyproline uptake and utilization

Isozymes

Compare fitness of predicted isozymes for: 3.4.13.9

Use Curated BLAST to search for 3.4.13.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2C1Y4 at UniProt or InterPro

Protein Sequence (401 amino acids)

>ABZR86_RS20500 Xaa-Pro peptidase family protein (Dyella japonica UNC79MFTsu3.2)
MSSSQIGGLDLAQARSRLRPWQATAPAIGADEYQHRLEHARALLRAQRIDALLVTAGISL
RYFTGVAWGASERLVGMLLTAHGDPILICPGFEAGSLAAVLRVPADVRLWEEHEDPQQLV
ADALAERGAGSLALDPAAPFLVAERLRAVLGGKPIADATAIVDGCRMCKSPAELALMKQA
TAMTLEVHRFAAGLMREGISRTELVRFIDEAHRAMGADNGSSFCIVQFGHATAYPHGIPG
EQYLERDQLVLIDTGCTVQGYHSDITRTYAFGTPTAEQARIWALEQAAQRAAFEAVRPGV
SCAAVDDAARAVVERAGLGPDYRLPGIPHRTGHGCGMAIHEMPYLVRGSRTALRPGMCCS
DEPMIVVPERFGIRLEDHFYVTDDGAAWFTPPSPAIDQPFA