Protein Info for ABZR86_RS20280 in Dyella japonica UNC79MFTsu3.2

Annotation: chemotaxis protein CheA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 transmembrane" amino acids 103 to 114 (12 residues), see Phobius details PF01627: Hpt" amino acids 8 to 99 (92 residues), 60.2 bits, see alignment E=3.9e-20 PF02895: H-kinase_dim" amino acids 256 to 313 (58 residues), 50.9 bits, see alignment 3.5e-17 PF02518: HATPase_c" amino acids 363 to 502 (140 residues), 68.5 bits, see alignment E=1.3e-22 PF01584: CheW" amino acids 508 to 630 (123 residues), 75.2 bits, see alignment E=8.1e-25

Best Hits

KEGG orthology group: K03407, two-component system, chemotaxis family, sensor kinase CheA [EC: 2.7.13.3] (inferred from 51% identity to tgr:Tgr7_1341)

Predicted SEED Role

"Signal transduction histidine kinase CheA (EC 2.7.3.-)" in subsystem Bacterial Chemotaxis or Flagellar motility or Two-component regulatory systems in Campylobacter (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3, 2.7.3.-

Use Curated BLAST to search for 2.7.13.3 or 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2I5K7 at UniProt or InterPro

Protein Sequence (650 amino acids)

>ABZR86_RS20280 chemotaxis protein CheA (Dyella japonica UNC79MFTsu3.2)
MDPSLDSELRDDFLVEAGELVQRLGEQLVALEEAPRDAELLNAVFRAFHTVKGGAGFLGI
DPMVQLCHHAEDLLNEARAGHVLIDAARMDALLEALDLVNAMMAALASSSAMPVAPAALL
VRLQPHAVRPPAPAPAPVPAPAPVAEESGTIDDSEFEALLDSLYGMGGAPGAPVQPPASD
MIDDTEFEKLLDDLHGKGKAPGTPAPSSSNTIDDSEFEALLDSLHGKGAAPGSAAKAAAA
PAPAKAAAKAAPPPEATVRVDTGRLDALVNRAGELVLVRNRLLSLAASSGDEPFATAAGE
LDRVADELQGAVLGMRMQPVGRLFQRFPRIVRDLARQLGKEIELVLEGEDTDLDRSLVEA
LADPLIHLLRNAVDHGLETPDVREGSGKSRKGRVRLAASQRGERIVIVVADDGRGMDPDI
LRRKAMEKGVIDAAQAARLSETECLELIFRPGFSTAAQVSDISGRGVGMDVVKTRVAELG
GTLQVRSKLGQGSELELTVPLTLAIVRVLMVRVGTRLFAMPLSNVDEVFELSPGQDRLLD
GCLIAAHRERALPLGDLAAWSAAAPTPGRHVVVLHIGHQRLGCLVHDVLGREDVMVKPLG
PLFAGTAGVAGATITGDGRLALVLDLAGLAGEGGPWQLATRVSLSPEAVV