Protein Info for ABZR86_RS20010 in Dyella japonica UNC79MFTsu3.2

Annotation: gamma-glutamyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 578 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details TIGR00066: gamma-glutamyltransferase" amino acids 53 to 569 (517 residues), 437.3 bits, see alignment E=3.6e-135 PF01019: G_glu_transpept" amino acids 65 to 571 (507 residues), 538.6 bits, see alignment E=9.1e-166

Best Hits

KEGG orthology group: K00681, gamma-glutamyltranspeptidase [EC: 2.3.2.2] (inferred from 55% identity to psu:Psesu_1196)

Predicted SEED Role

"Gamma-glutamyltranspeptidase (EC 2.3.2.2)" in subsystem Glutathione: Biosynthesis and gamma-glutamyl cycle or Utilization of glutathione as a sulphur source (EC 2.3.2.2)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.3.2.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2HZ26 at UniProt or InterPro

Protein Sequence (578 amino acids)

>ABZR86_RS20010 gamma-glutamyltransferase (Dyella japonica UNC79MFTsu3.2)
MRFLVKLPALRARAVLLGLLLVSGAACADSPRTVPAAAKAATAQKGPGKAAIASANFHAT
EAGLEVIAKGGNAFDAAIAVAATLSVVEPESSGIGGGFMAVLHRAADGKQIFIDARETAP
AAVNAKDYLAADGSPNRDAALNGPLSAGIPGEPAGLAWLAKHYGKLPLKESLAPAVRIAR
DGFEPDSRLLNAIEERQKDIQRWPASVAKFLPGGKLPAKGETWRDPGQARTLELLGEQGH
DGFYRGEVAQKLVAAVQAAGGHWTAKDLESYQVKERAPIVVDYRGYRIVTAPPPSSGGVA
VAEILNILSGFDLTKLDDAHRTHLVIEAMRRAFRDHNDYLGDPDFVKMPLDMLLSPYYAA
GLRQTILPDKATPSAMLPASTGVDPGMHTTHFSVIDREGNIVSITLTVNYTLGSTFVADG
TGVLLNDEMDDFALVPDKPNVYGLLGSAANAPAPGKRMLSSMTPSIVFGADRVGVIGSPG
GSTIITQVLEGIMAFIDGKDALGIAGQKRFHHQYMPDRVDVEDGAFDAATTDALARMGYT
LKQRSPWGYMNVVTWDLKNGRLDAASDPRRPSGLGKVQ