Protein Info for ABZR86_RS19750 in Dyella japonica UNC79MFTsu3.2

Annotation: ATP-dependent DNA helicase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 641 PF00270: DEAD" amino acids 34 to 85 (52 residues), 28.9 bits, see alignment 1.4e-10 PF13307: Helicase_C_2" amino acids 464 to 621 (158 residues), 150 bits, see alignment E=1.1e-47

Best Hits

KEGG orthology group: K03722, ATP-dependent DNA helicase DinG [EC: 3.6.4.12] (inferred from 55% identity to mca:MCA1991)

Predicted SEED Role

"DinG family ATP-dependent helicase YoaA" in subsystem DNA repair, bacterial DinG and relatives

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.12

Use Curated BLAST to search for 3.6.4.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2HW59 at UniProt or InterPro

Protein Sequence (641 amino acids)

>ABZR86_RS19750 ATP-dependent DNA helicase (Dyella japonica UNC79MFTsu3.2)
MTDSDISALLGADGPFARELPNFAPRAAQQAMARAVEHAIAERETLIAEAGTGTGKTYAY
LVPALLSGERVIVSTGTKALQDQLYFRDLPKVRSVLGARLKTALLKGRANYLCLYRLDQT
VREGASFDRLQASQLAAIRAWSARTKQGDRMELAEVPEESPMWPRVTSTPENCLGVECPF
FDDCHVVKARREAQEADLVVVNHHLLFADLALKQEGFGEILPGAQAFILDEAHQVPELAG
QFFSQSISARQLTELAQDALGECNGITGAIGLVLEPVESLREAVRKLRLALDALPERGPF
HLLEQSSTVREALHDVRELLAALTDVLASQAERSRGFANAHERAALYSERLDRIVEQANE
QDVRWYELFPRGFALHATPLDLAAPMRALRERAQAAWIHTSATLSVAGQFGHFARQLGLD
DPVTLSLESPFDYARQALCYLPPALPDPSARDYTERVVDAVLPVLHASNGRAFLLFTSHR
ALRRAAELLEGRVPWPLFVQGTAPRHRLLEDFRASGHGVLLGAASFWEGVDVAGEALSVV
VIDKLPFAAPDDPVLQARLDALEQAGINPFMGWQVPSAVIALKQGVGRLIRDVHDRGVLV
LCDPRLSTKGYGRLFLASLPPMPRTKELGDVQAFFAETTTM