Protein Info for ABZR86_RS19740 in Dyella japonica UNC79MFTsu3.2

Annotation: penicillin-binding protein 1B

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 775 transmembrane" amino acids 20 to 39 (20 residues), see Phobius details TIGR02071: penicillin-binding protein 1B" amino acids 29 to 740 (712 residues), 820.4 bits, see alignment E=6.6e-251 PF14814: UB2H" amino acids 66 to 150 (85 residues), 53.7 bits, see alignment E=2.6e-18 PF00912: Transgly" amino acids 156 to 333 (178 residues), 188 bits, see alignment E=1.6e-59 PF00905: Transpeptidase" amino acids 425 to 670 (246 residues), 77.6 bits, see alignment E=1.5e-25

Best Hits

KEGG orthology group: K05365, penicillin-binding protein 1B [EC: 2.4.1.129 3.4.-.-] (inferred from 48% identity to xac:XAC3109)

Predicted SEED Role

"Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-)" in subsystem Peptidoglycan Biosynthesis or Type IV pilus (EC 2.4.1.129, EC 3.4.-.-)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.129, 3.4.-.-

Use Curated BLAST to search for 2.4.1.129 or 3.4.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2JZ28 at UniProt or InterPro

Protein Sequence (775 amino acids)

>ABZR86_RS19740 penicillin-binding protein 1B (Dyella japonica UNC79MFTsu3.2)
MAFLTRLRSLASAIWPWVRIPFWIGLGLFFGFVLPYTLVLNKRVQDRFNDLVFAVPTRVY
ARPLPLEAGAPMTPGALELELTFAGYGNDGHGQVAGTWAKDGSSYVISSRGYAGPDGGEL
PHRIRVTLGKNAVASVKDAASGKALDLAHLDPARIATVYGSQQEERRIVRLADVPPMLIA
GLQAVEDRDFKHHIGIDFSAILRASFANLRAGHTVQGGSTLTQQLVRNLFLDRDQNITRK
FNEALMSILIEAHYDKGRILEAYVNQVFLGQQGGQAVHGFAAASEFYFGRRMEDLRPQEM
ALLIGMVKGPSFYDPRRYPERALSRRNLVLEQFAGTGLLTPEQAKAAEATPLGIVSNGQL
PHNRFPAFMQLVRAQITNDFDDATLSAGNLSIFTTLDPAAQLYAEQGIATAMGGLGKRGE
AAQAAAVVTEAQTGSVLAIVGSKDPGDQGFNRAIDARRSIGSLIKPLVYLVALAQPERWN
LGSPVEDTPISMRQPDGTQWTPKNDEGDVHGSVPMVDALVHSWNLATIHLGLEVGLPRIK
SFLESFGLEDVNPSPSLLLGAQGIPPLQVAQLYQYIAADGHALPLVAVRGVVDADGKTVK
RYEVKTGKGEYQLAVRQVTWAMQQVVRSGTAAAIGKTLPSLNAAGKTGTSNEMRDSWFAG
FTGDHLAVFWMGRDDNKPSGLYGATGSLRAWQELFRKLPSKPLSAAPGEGLEMAWINPTD
GKRTDPSCEGARQIPVVAGTLAQDSEGCFWQRVQNWFGGDDNKSPAPASTAPIRD