Protein Info for ABZR86_RS19095 in Dyella japonica UNC79MFTsu3.2

Annotation: hybrid sensor histidine kinase/response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1199 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details transmembrane" amino acids 781 to 802 (22 residues), see Phobius details PF07494: Reg_prop" amino acids 55 to 77 (23 residues), 18.7 bits, see alignment (E = 4.4e-07) amino acids 200 to 217 (18 residues), 16.5 bits, see alignment (E = 2.2e-06) PF07495: Y_Y_Y" amino acids 711 to 773 (63 residues), 47.3 bits, see alignment 4.8e-16 PF00512: HisKA" amino acids 828 to 893 (66 residues), 77.5 bits, see alignment 1.9e-25 PF02518: HATPase_c" amino acids 940 to 1048 (109 residues), 99.1 bits, see alignment E=6.6e-32 PF00072: Response_reg" amino acids 1071 to 1183 (113 residues), 80.7 bits, see alignment E=2.7e-26

Best Hits

Predicted SEED Role

"Histidine kinase/response regulator hybrid protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2GFI5 at UniProt or InterPro

Protein Sequence (1199 amino acids)

>ABZR86_RS19095 hybrid sensor histidine kinase/response regulator (Dyella japonica UNC79MFTsu3.2)
MLSSLLLGLALLAPSASVADKAGSPHAPAAATAPAPNAAGVLPTPQFRRYGTFNGLPSSS
VYAVAQAPDGAMWFGTKGGIARYDGVAFKVYRHVADDPRSLHDNGIATLLFDRQGQLWAA
GLEAGLNRFDPVTQSFEHWSHDPARPESLASDKVWDAVVGPDGALWIGTQHGLDRMRPDG
SGFDHIAAPPPSDDPSGFGAVGALYVDPKGRLWIGTDEGVYVRDAEGRVSQVPQEDPKET
ISVWSIEGDGDEVRIAAAHGLLVVGADGVARKFDKDIADFNVLTSVRDRAGRLWIGTQRG
LYLQTRRSGPVKKVLDQPLLYGNLPGTWVWKIRQDREGGLWVALFDGGIGYLAPGWSGIS
RFTHIPEDADSLRDSVATSMARGHDGRVWVGERGGRVDKLDPVTGKSEHVVSDMRGDVIG
MTEDDQDRLWIATQGSLYRYARGKLDKVPTAERGMVHPLEVEVGPDGKLYARTFAEGLFR
VDQDTLEVTPVSFLPAEERTRWGAQLTLVDGVFWYASDGGLWRLDRSYDHFEPVPGIRND
RKVDAFIFTPDHKFLWMARPDALERYRREGDHFVLERRVDARQGWPSVNVADLALDKRGR
VWMLGRDGMRRFDPESGSFRTFGLQDGLSNGEFVRGYAAMPDGYIYAPTMGGVVAFNPDQ
TETEASSPQVAITGVSVRGRNGLQPAVLGHGPLELDWHARGLNIEARVFSYIDPAVNRYR
FHLEGLDTEWVDTGTRGEREFASLPPGDYTLTVMGAGADGVWGRLSAPLQVHVQAPPWER
WWAWCMYVLAVAMLAWMALLVWRRRLAQRHQMQLAEQRSRLAEQASAAKTQFLATLSHEI
RTPMTGVMGMAELLLNSGLGAQQHEYAEAIQRSGQMLLKLLNDALDLARIEAGKLSLDLA
PFDPRALLRDVAALEQGQARAKGLAFKLEIADDLPARVMGDALRVQQILLNLANNALKFT
ERGSVILRARREGNELRFSVIDTGPGIPEASQARLFQRFEQANGPQRRAGSGLGLAICRE
LVALMGGHIELESKVAHGSSFHVHLPLEVVQEDVAASAAPVRAPGASGLCVLLVEDDAII
AAVVRGLLERQGHQVRYVGNGLAAMTELAQGDADAMLLDLDLPGVDGFQIARLIRQRETA
GAHLPIIAITARSGGDEEERARAAGMDGFLRKPLTGEQLAEALATVVVAERHVEPAAYP