Protein Info for ABZR86_RS18930 in Dyella japonica UNC79MFTsu3.2

Annotation: EAL domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 964 PF13185: GAF_2" amino acids 148 to 293 (146 residues), 36.4 bits, see alignment E=1.5e-12 amino acids 348 to 486 (139 residues), 54.4 bits, see alignment E=4.1e-18 PF01590: GAF" amino acids 208 to 292 (85 residues), 29.1 bits, see alignment E=3.4e-10 amino acids 359 to 485 (127 residues), 38.9 bits, see alignment E=3.1e-13 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 534 to 698 (165 residues), 136.3 bits, see alignment E=4e-44 PF00990: GGDEF" amino acids 538 to 694 (157 residues), 162.2 bits, see alignment E=2.2e-51 PF00563: EAL" amino acids 716 to 948 (233 residues), 234.7 bits, see alignment E=2.5e-73

Best Hits

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2GBJ9 at UniProt or InterPro

Protein Sequence (964 amino acids)

>ABZR86_RS18930 EAL domain-containing protein (Dyella japonica UNC79MFTsu3.2)
MSSVPTNAAPMYPPPEPGSAALHAAVEGLFRAGDAAAVMEICGTMIRALGVRGSLVWRQL
EAPADPLLPGQLALAEDPQCQRLLAVATEGPLPAGAAEEIAWLGRMAASRLRQLAETSRL
YEAISRLAMAERLQRALYAIADQASTEHNMAEMMHALHGILGSLMYAENFYVALYDPATD
SVRFPYYVDTMDKDPPLPDQSVPLQDMRHSLTWNLLQSGQPIMGSVEELSRQFAGQFVLL
GPVCEDWLGVPLQRDGRVVGGIVVQSYREDTHYTEHDRELLSYVAKHVQTALERREAHAE
LERRVASRTAALREANRVLRQQVLQRQRGERLQAALFRIAELANASESLDNFYAAVHRVI
GGLLYARNFYIALLDEEPNQLTFPYSVDEFDTVRLPRSHGRGLTEYVLRHGKPLLASPDD
IDRLARQGEIGHHGSRSVCWLGVPLIWGERAMGVLAVQSYSPEHTYDVRDQELLTFVSYH
VANALQRKHTTESLKQAYASLERRVTERTRALALANRDLREQIAERERVERRLKYETLHD
SLTGLPNRTLLLQRLEQALQRYHGNPNDMFAVLFIDLDRFKVINDSVGHLVGDDLLFQVG
GRIRACLKTRDVVARLGGDEFAVLAEGITDYRMALVIAERIIAELQTPFRLGAKEIFTSA
SIGIALPGPHYQRPEELLRDADAAMYRAKDEGRHRAAVFDDRLRREALSLLEMEGDLRRA
LSRNEFVPFYQPIVSLEDGRTVGYEALLRWRHPDRGLLTPSDFLAVAEESGCSESIDWQI
FEQVCAQAEALTGSDGFVSINVSGRHFRSPDLDRRLLDLLAAHRLPTRCLRIEVTERALL
ENASQVKRILENLRDHDVGIALDDFGTGYSSLSYLHQYPISTLKVDRSFITELPREGGHS
LAVVRAIQVLADSLQMQVIAEGIEQENQRDALLRVGCRYGQGFLFATPHAADVWLQREYH
FALP