Protein Info for ABZR86_RS18710 in Dyella japonica UNC79MFTsu3.2

Annotation: glutamine--fructose-6-phosphate transaminase (isomerizing)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 609 TIGR01135: glutamine-fructose-6-phosphate transaminase (isomerizing)" amino acids 2 to 609 (608 residues), 821.7 bits, see alignment E=2e-251 PF13522: GATase_6" amino acids 65 to 182 (118 residues), 70.7 bits, see alignment E=1.9e-23 PF13537: GATase_7" amino acids 87 to 196 (110 residues), 52.8 bits, see alignment E=5.8e-18 PF01380: SIS" amino acids 292 to 417 (126 residues), 104.4 bits, see alignment E=6.3e-34 amino acids 461 to 591 (131 residues), 84.2 bits, see alignment E=1.1e-27

Best Hits

Swiss-Prot: 59% identical to GLMS_PSEPK: Glutamine--fructose-6-phosphate aminotransferase [isomerizing] (glmS) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)

KEGG orthology group: K00820, glucosamine--fructose-6-phosphate aminotransferase (isomerizing) [EC: 2.6.1.16] (inferred from 61% identity to mca:MCA0015)

MetaCyc: 58% identical to L-glutamine--D-fructose-6-phosphate aminotransferase (Escherichia coli K-12 substr. MG1655)
Glutamine--fructose-6-phosphate transaminase (isomerizing). [EC: 2.6.1.16]

Predicted SEED Role

"Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16)" in subsystem Sialic Acid Metabolism or UDP-N-acetylmuramate from Fructose-6-phosphate Biosynthesis (EC 2.6.1.16)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.6.1.16

Use Curated BLAST to search for 2.6.1.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2GA93 at UniProt or InterPro

Protein Sequence (609 amino acids)

>ABZR86_RS18710 glutamine--fructose-6-phosphate transaminase (isomerizing) (Dyella japonica UNC79MFTsu3.2)
MCGIVAATAQRDVAPLLIAGLKALEYRGYDSAGLAVLQEGEIRRVREKGKVREMESQYLA
DPFPGGTGIAHTRWATHGVPNKVNAHPHIAGHVALVHNGIIENYASLRSELESRGHAFTS
ETDTEVMAALIGERLASGKSLLDAVSSVVHELEGAYAIAVISDKEPGRVIGARRGAPLLV
GVGIGENFLGSDAQALIQVTNRMIYLEEHDVVEITRDRVRIFGQHGEAVERTIHESELST
DAVERGEYRHYMQKEIFEQPRAVADTLEARIGPHGVLPNIFGVNGDELLGKTKGLHIIAC
GTSYHAGLVAKYWIEDYARLPVNVEVASEYRYREAVVPDGTLFVAISQSGETADTLAAMR
ESRRRGYLGTLAICNVPESSVVREADLKLMTRAGPEIGVASTKAFTTQLAALGLLALQLA
RHRGLDDARYADLTAQLQSLPKKIEKALELEPQIVDLAEHLIHRQHALFLGRGAQYPVAM
EGALKLKEISYIHAEAYAAGELKHGPLALVDEDMPVIAVAPNGPLLDKLKSNLQEVRARG
GELLVFADGAASMDGNAARGSILRIDGGGDFIAPAVFTVPMQLLAYHVAVLRGTDVDQPR
NLAKSVTVE