Protein Info for ABZR86_RS18400 in Dyella japonica UNC79MFTsu3.2

Annotation: sensor domain-containing diguanylate cyclase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 720 transmembrane" amino acids 12 to 33 (22 residues), see Phobius details amino acids 39 to 56 (18 residues), see Phobius details amino acids 63 to 81 (19 residues), see Phobius details amino acids 87 to 106 (20 residues), see Phobius details amino acids 125 to 148 (24 residues), see Phobius details amino acids 160 to 181 (22 residues), see Phobius details amino acids 195 to 211 (17 residues), see Phobius details amino acids 215 to 230 (16 residues), see Phobius details amino acids 237 to 260 (24 residues), see Phobius details amino acids 272 to 293 (22 residues), see Phobius details PF05231: MASE1" amino acids 17 to 286 (270 residues), 59.8 bits, see alignment E=7.5e-20 TIGR00229: PAS domain S-box protein" amino acids 303 to 428 (126 residues), 41.3 bits, see alignment E=1.5e-14 amino acids 430 to 552 (123 residues), 52.6 bits, see alignment E=5.1e-18 PF08447: PAS_3" amino acids 331 to 400 (70 residues), 43.3 bits, see alignment E=1.1e-14 PF08448: PAS_4" amino acids 440 to 544 (105 residues), 38.7 bits, see alignment E=3e-13 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 553 to 713 (161 residues), 146.7 bits, see alignment E=5.3e-47 PF00990: GGDEF" amino acids 556 to 710 (155 residues), 158.4 bits, see alignment E=3.9e-50

Best Hits

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2JLN0 at UniProt or InterPro

Protein Sequence (720 amino acids)

>ABZR86_RS18400 sensor domain-containing diguanylate cyclase (Dyella japonica UNC79MFTsu3.2)
MQLRIEPNLRWTRWAEALALLVAVLGATAYSLLLTRHTGTNVTMWIANGVVVGALLRVPD
ERWPLYLVAAFVGYFAGKMLLGDPLLSSALLGLVHGVEVMIVARGVRWRFPRIEDDTPFL
RLGQVAMLSTLVASLVSAGLAAFMLYAFNNTDFWTTFDWWFRAHLLGMVIVATLTLVVLV
QGWRMLGQPGHRLRLLRDLLLLGATTAGVFAQSRYPLLFVVFGPLFYVVIRHRFPGLVIG
VAVVTLIVNIAIAMGGGPLSLIPGSSPVERSLLGQSFLGMVCLVAVPIALAQADRRRLTR
RVRDSEVRYRLLADYASDLVMRIARDGTRRYVSPSIKDLLGWEVGEFMLPRPDLIHADDR
ERVAEAVVQLWDTGKVSLTRYRLRHKKGYYVWIEALVRVAPSPDHPGEMELIYTGRDITE
SIVAEQALADSETRLRRITDKVPALITHVGNDERYIFVSGYAREITGLEPEAMVGRSVRE
TRGAALYSLMKPHIAAVLQGRETTFEYEFERDGRYFYLQATYLPATSVTGESIGFYALTT
DVTRIKLAEQKLSFLAHYDTLTNLANRRYFTECAQAALDRASVTRAPMLLMLIDVDYFKQ
INDGHGHAAGDAVLREVARRLKASVRKSDLVARLGGDEFVILCDDVDATYAAESLANKVI
TSMGAPVSLDAARLKVTLSVGAALCRDVFSLDELVQKADEALYEAKEAGRACYRLVVEGL