Protein Info for ABZR86_RS17545 in Dyella japonica UNC79MFTsu3.2

Annotation: DegQ family serine endoprotease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 457 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details TIGR02037: peptidase Do" amino acids 40 to 450 (411 residues), 458.2 bits, see alignment E=1.5e-141 PF00089: Trypsin" amino acids 91 to 249 (159 residues), 72.5 bits, see alignment E=1.2e-23 PF13365: Trypsin_2" amino acids 92 to 227 (136 residues), 117 bits, see alignment E=3.1e-37 PF00595: PDZ" amino acids 264 to 345 (82 residues), 43.3 bits, see alignment E=9.9e-15 PF13180: PDZ_2" amino acids 266 to 357 (92 residues), 51 bits, see alignment E=3.6e-17 PF17820: PDZ_6" amino acids 292 to 346 (55 residues), 34.4 bits, see alignment 3.8e-12

Best Hits

Swiss-Prot: 48% identical to DEGQ_ECOLI: Periplasmic pH-dependent serine endoprotease DegQ (degQ) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 54% identity to tgr:Tgr7_2953)

MetaCyc: 48% identical to periplasmic serine endoprotease (Escherichia coli K-12 substr. MG1655)
3.4.21.-

Predicted SEED Role

"HtrA protease/chaperone protein / Serine protease (Protease DO) (EC 3.4.21.-)" (EC 3.4.21.-)

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.-

Use Curated BLAST to search for 3.4.21.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2IYL5 at UniProt or InterPro

Protein Sequence (457 amino acids)

>ABZR86_RS17545 DegQ family serine endoprotease (Dyella japonica UNC79MFTsu3.2)
MSHRRIRPFAALFAALLGTAVPLASQASLPATVDGQALPSLAPMLEKVTPAVVNISTKTR
VQVRDPFFDDPVFRQFFGLPGQQRERVAQSLGSGVIVDAAKGYILTNNHVVGGADDITVS
LQDGRDFKGKLIGTDPDTDVAVVQIQATGLQALPVADSSKLRVGDFVVAVGDPFGLSQTV
TSGIVSALGRSGLGGTGYQNFIQTDASINPGNSGGALVNLRGELVGINTMIFSPSGGNVG
IGFAIPTNLSRDVMEQLIAHGKVSRGNLGVETQDITPRIAQVLGLKNTSGAVVTRVSAGS
AADGADIETGDVITAIDGKPLRNAQELRNAEGLLPVGSTVKLTLQRNGASREVTAKLTPE
KLATVDGATLDPRLAGVMFSELSQSLRGQGVAGVAVQSVKPGSRAALAGLGTNDVVIGVG
NARIPNLATMKRLAGVKPRQLVLVVSGDEGVRYVDVR