Protein Info for ABZR86_RS17150 in Dyella japonica UNC79MFTsu3.2

Annotation: bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 952 PF03710: GlnE" amino acids 39 to 280 (242 residues), 210.6 bits, see alignment E=2.6e-66 amino acids 556 to 802 (247 residues), 209.2 bits, see alignment E=7.2e-66 PF08335: GlnD_UR_UTase" amino acids 301 to 439 (139 residues), 104.1 bits, see alignment E=6.7e-34 amino acids 826 to 921 (96 residues), 26.4 bits, see alignment E=6.3e-10

Best Hits

Swiss-Prot: 52% identical to GLNE_STRMK: Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme (glnE) from Stenotrophomonas maltophilia (strain K279a)

KEGG orthology group: K00982, glutamate-ammonia-ligase adenylyltransferase [EC: 2.7.7.42] (inferred from 52% identity to sml:Smlt0473)

Predicted SEED Role

"Glutamate-ammonia-ligase adenylyltransferase (EC 2.7.7.42)" in subsystem Ammonia assimilation (EC 2.7.7.42)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.42

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2HQS7 at UniProt or InterPro

Protein Sequence (952 amino acids)

>ABZR86_RS17150 bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase (Dyella japonica UNC79MFTsu3.2)
MQPKESPALRALIDDRYAELAARCRLAGVALHDDAGVAERIRRALLASDFAYDIWFRQPQ
LLAPQGLERLRAGGDASTRSEALKLDPDEAVCMATLRRFRHAEALRLVFRDVNGLDELPE
TLSATSVLYEVLLGAALGWSERALASRYGHSRDHDGALQRMVVVGFGKLGGTELNFSSDI
DLVLAYPHSGQSDGPRPLDNSEYFVRMGRQLVRLLAEPTVDGICARVDLRLRPFGNAGRL
ALPFSAMEQYYQSEGRDWERYAWIKARAVAGDRNAGKQLQELLRPFVYRKYLDYTAFAGL
REMKALIDAEVARKDLADNLKLGPGGIREVEFIVQLTQLIRGGREPSLRVRGLLPALTAC
EARGHIAAARAKALREAYVFLRKVENRVQMLRDAQTHDIPQDALSRERIALGLGHASWEE
LEAELARHRAVVSEEFAEVLVPQGGRTASVPAEDVALWQRVCAEEVSPGVLEAAGFQPGA
DAAEALLKLPQAAAVRAMPARSREQLDRLMPQLLALARDSAAPVPCLLRLCRLVQAVARR
SSYLALLEEQPAARRRLADLFARSAFLAERVIAQPLLLDDVLDPRIDQLPLKRADISAEI
SRVLGTLDEREAEAELERINEFKASTAFRLGLAFNDGRADAVATARRLGALAESVVIAVT
ALAERELTEQHGRLPGEGSGFAVLGYGSLGGEELGFASDLDLVFVYDTRRAHLMSDGARP
IEGSRWYQRLAQRVMNWLTVLTRAGRLYEVDTRLRPDGSKGLLVSSLEAFAEYQRSRAWT
WEHQALQRARPVAGDAALNAELVEVRRGILAVPREHARVLADVSDMRRRWRAERDRSDER
QFDLKQGHGGLLDIEFALQGLVLAHAAERPLLLMSTANAALIEACRTSGLLDAAQADVFA
RAHGELLRRALACTLDLRSRIAARDPELDALGAEVRRVTAELGFAFGQALPA