Protein Info for ABZR86_RS17015 in Dyella japonica UNC79MFTsu3.2

Annotation: DNA polymerase I

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 908 PF02739: 5_3_exonuc_N" amino acids 3 to 164 (162 residues), 181.2 bits, see alignment E=2.5e-57 TIGR00593: DNA polymerase I" amino acids 4 to 908 (905 residues), 927.7 bits, see alignment E=4.5e-283 PF01367: 5_3_exonuc" amino acids 165 to 258 (94 residues), 106.8 bits, see alignment E=1.4e-34 PF01612: DNA_pol_A_exo1" amino acids 311 to 498 (188 residues), 117.9 bits, see alignment E=8.8e-38 PF00476: DNA_pol_A" amino acids 532 to 906 (375 residues), 527.5 bits, see alignment E=4e-162

Best Hits

KEGG orthology group: K02335, DNA polymerase I [EC: 2.7.7.7] (inferred from 67% identity to xal:XALc_0119)

Predicted SEED Role

"DNA polymerase I (EC 2.7.7.7)" in subsystem DNA-replication or DNA Repair Base Excision (EC 2.7.7.7)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2HR60 at UniProt or InterPro

Protein Sequence (908 amino acids)

>ABZR86_RS17015 DNA polymerase I (Dyella japonica UNC79MFTsu3.2)
MSKLILIDGSSYLYRAFHALPPLTNAQGEPTGALFGVVNMLRSTLKARPEYVAFVSDAPG
PTFRDAMYDQYKANRPPMPQDLGAQVEPMLAIVSALGFPILRVTGVEADDVIGTLAVQAH
ARGIEVEISTGDKDLAQLVRPGVTLVNTMTNTTMDDAGVMEKFGVRPEQIIDYLTLVGDS
VDNVPGVPKCGPKTAAKWLAEYGSLDGVIANADKVGGKIGESLRAALPQLPLSRELVTVR
LDVPLEQGVEALKLRERDADKLRELYTRYEFKAALKELEGGESAAAAPVPTAAPAVAPAQ
PADDLSGPGRYELVATEAQLDAWVDKLRSAELIAFDTETTSIDAMRADIVGLSLAVETGE
ACYIPVAHDFPGAPAQLPRELVLAKLKPIFEDPARPKLGQHAKYDINMLSHYGIVLQGLK
HDSMLESYVWNATATRHDMDSLARKYLGYETVKYEEVAGKGAKQISFSQVDLDTACRYAA
EDADITLRLHRALWPLLEHVPRLRSVYEDIEIPLVPVLAGMEQRGVLIDVASLRLQSQQL
GKRMLELQQQAWKTAGHDFSLDSPKQLQSVLFDELGLPAKLRTPTGQPSTNEEALEAIAD
EHPLPRLILDYRGLAKLRSTYTEKLAEIVNPRTGRVHTSYHQGAVATGRVSSSDPNLQNI
PVRTEEGRRIRQAFIAPPGWKVMAADYSQIELRIMAHLSGDEGLMRAFQEGGDVHRATAA
EVFGLAPEEVSANQRRAAKAINFGLMYGMSAFGLARQLGVDRGEASDYMARYFARYPGVH
AFMDATREQAHRDGYVETIFGRRLYLENLTNRNQALRAGAERAAVNAPMQGSAADIIKRA
MISVAAWLKGRDDAHMLMQVHDELVFEVHEDAVDEVRAAVVARMSGAAELRVPLLVEAGV
GANWDEAH