Protein Info for ABZR86_RS16990 in Dyella japonica UNC79MFTsu3.2

Annotation: TIM-barrel domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 758 PF01055: Glyco_hydro_31_2nd" amino acids 206 to 516 (311 residues), 222.7 bits, see alignment E=1.3e-69 PF21365: Glyco_hydro_31_3rd" amino acids 527 to 614 (88 residues), 81.6 bits, see alignment E=7.2e-27 PF17137: DUF5110" amino acids 630 to 699 (70 residues), 46.1 bits, see alignment E=6.4e-16

Best Hits

Predicted SEED Role

"Alpha-glucosidase (EC 3.2.1.20)" in subsystem D-Galacturonate and D-Glucuronate Utilization or Maltose and Maltodextrin Utilization (EC 3.2.1.20)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.20

Use Curated BLAST to search for 3.2.1.20

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2HWJ4 at UniProt or InterPro

Protein Sequence (758 amino acids)

>ABZR86_RS16990 TIM-barrel domain-containing protein (Dyella japonica UNC79MFTsu3.2)
MTAMAQASEELRPSPVGFQVAQGTVTVHYLSPDIVRLSFVPKDGAPAPPTVVIDPALDSE
TSGGSDPSLRGAVRDGAWVVQRDGRVLLSIDLAALGRGEVQARHAATDPLYGIHGYGAFE
RADGGLQRNGKQVAKAGEQGNAGAPFVWSTAGYGLLADAEGASFDLDGGKLRVRGRQGQA
IGDVYVFIGEPKAIFAALARVSGRSPLFPKWAMGFTNSQWGIDQRELLQLVDTYRENHIP
IDNFTLDFDWKAWGADPYGEFRWNPDKFPGGSDGSLKTMLDAKGMHLTGIMKPRLHVDTA
EGRYATEHGLWAAKSKAAPDYFSHQTVRDLDFDRPAARAWFFNDALKHSFDTGMAGWWND
EADTLDSDTQFLNMQRALYDGQRAYGNRRVWSINRNFYLGSQRYAYGLWSGDIATGFASM
KAQRQRMLSAINAGAMQWGMDGGGFQKSSKQADPVTGGLTPENYARWIQFGAFTPIFRVH
GELGIKRQPWIYGPVAEKAATAAIRLRYALLPYIYSYEYQRRATGVGLVRPLLFDWPDDA
RVREDVDAWMFGDYLLVSPVVEAGQASKDIYLPAGRWVDYASGKSHDGGQTIHYALDAKR
WSDLPLFVREGAIVPMQAPEDYVGQHALRELEVDVFPADRRTSFPYYDDDGVTYGYEHGD
YFLQTLAVQRTQQGVSFETAAPEGRFKPALAWYVVKMHGIAAAAVSSDGKPLGEAASEEA
LRARDGAGWARGTDRFGPVTWVRMQAGRVERIALTPVR