Protein Info for ABZR86_RS15515 in Dyella japonica UNC79MFTsu3.2

Annotation: nitrogen regulation protein NR(I)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 462 TIGR01818: nitrogen regulation protein NR(I)" amino acids 5 to 452 (448 residues), 600.1 bits, see alignment E=1.4e-184 PF00072: Response_reg" amino acids 5 to 113 (109 residues), 83.7 bits, see alignment E=2.7e-27 PF00158: Sigma54_activat" amino acids 137 to 304 (168 residues), 224.4 bits, see alignment E=1.8e-70 PF14532: Sigma54_activ_2" amino acids 138 to 308 (171 residues), 80.6 bits, see alignment E=3.4e-26 PF07728: AAA_5" amino acids 160 to 278 (119 residues), 31.3 bits, see alignment E=4.9e-11 PF02954: HTH_8" amino acids 414 to 451 (38 residues), 40.1 bits, see alignment 5.9e-14

Best Hits

Swiss-Prot: 52% identical to NTRC_KLEPN: DNA-binding transcriptional regulator NtrC (ntrC) from Klebsiella pneumoniae

KEGG orthology group: K07712, two-component system, NtrC family, nitrogen regulation response regulator GlnG (inferred from 61% identity to psu:Psesu_0094)

Predicted SEED Role

"Nitrogen regulation protein NR(I)" in subsystem Ammonia assimilation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2GMF7 at UniProt or InterPro

Protein Sequence (462 amino acids)

>ABZR86_RS15515 nitrogen regulation protein NR(I) (Dyella japonica UNC79MFTsu3.2)
MSEEIWIADDDRGVRFVLAEALRDAGLAVREFGDAESVREALRDARPALLLTDVRMPGEG
GLALLNDLKARGVGPVIVMSAFTDVATTAAAYRAGAADYLAKPFDLDQAVAAVQRALADV
PAAAAPPPAPVVPAHALLGESPAMREVFRLIGRVAASELNVLITGETGTGKELVARALHE
ESARRERAFVALNTAAIPSELLESELFGHEAGAFTGATRRYAGRFEQAEGGTLFLDEIGD
MPLALQTRLLRVLAGGEFYRVGGRELIRGNVRIVAATHQDLDARVAAGLFRADLKHRLDV
VRIELPALRQRRADIPLLAQHFLAAAARELKLPPKRFSKAALKAVAQRDFPGNVRELENL
CRRLAVIAPGVEILPADLGGPAAAPALGDWTDALREWAALALADGESDIHARAREAMDHT
LMQAALAVHGGHRQHAAAALGVGRNTLTRKLGASRTRRPSRP