Protein Info for ABZR86_RS15120 in Dyella japonica UNC79MFTsu3.2

Annotation: membrane protein insertase YidC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 576 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details transmembrane" amino acids 385 to 405 (21 residues), see Phobius details amino acids 449 to 471 (23 residues), see Phobius details amino acids 494 to 513 (20 residues), see Phobius details amino acids 528 to 550 (23 residues), see Phobius details TIGR03593: membrane protein insertase, YidC/Oxa1 family, N-terminal domain" amino acids 4 to 381 (378 residues), 323.1 bits, see alignment E=3.4e-100 PF14849: YidC_periplas" amino acids 82 to 374 (293 residues), 272.2 bits, see alignment E=7.8e-85 TIGR03592: membrane protein insertase, YidC/Oxa1 family" amino acids 384 to 564 (181 residues), 223.7 bits, see alignment E=2.2e-70 PF02096: 60KD_IMP" amino acids 385 to 564 (180 residues), 202.7 bits, see alignment E=3.8e-64

Best Hits

Swiss-Prot: 45% identical to YIDC_THISH: Membrane protein insertase YidC (yidC) from Thioalkalivibrio sulfidiphilus (strain HL-EbGR7)

KEGG orthology group: K03217, preprotein translocase subunit YidC (inferred from 45% identity to tgr:Tgr7_3318)

Predicted SEED Role

"Inner membrane protein translocase component YidC, long form"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2GI21 at UniProt or InterPro

Protein Sequence (576 amino acids)

>ABZR86_RS15120 membrane protein insertase YidC (Dyella japonica UNC79MFTsu3.2)
MNQTRTFLIFALLAVAYLLWMDWEKDYGPKPAPAPVASASTAAVPSADNGGSVPGATSTT
GAPATVPANGGSATAEAKAQLITISTDVLRLTVDTRGGSVVRSELLHYPSAPVTKKDPSP
PPVRLLDEQSEHFFVAQSGLATAQGNGASVAPTHLSVFQSAQTAYQLAEGQNELKVDLTW
QDAAGLKVTKTYALKRGSYDVSMDQKIENGSTVAWQGNAYEQLQRAGQPNNRSWLQNYTD
PAAHSFFGAGWYSPQDKFETLPFTDFQKKPLTRSITGGWAAMLQHYFVVAWIPPAQEANG
YSTSVVNPDTAQPYYLIRTVGPSLSVAPGQSLTSASRLYLGPKLQGTLDQIAPGLELSTN
YGWLTVIAQPLHWLLSKLHAISGNWGVAIILLVLLLKAALWKLTAAQFRSGARMRKLQPR
VTALKERYGDDKMKMQQAMMELYKKEKVNPMAGCLPILVTFPVFLGLYRVLMESVELRQA
PFFGWIHDLSAPDPFFVLPAIYVLVMLATQWLTPTTGMDPTQAKMMKVMPILFAVLFAFF
PSGLVLYWVVNGATSLAQQWFITRQVDRADHKVKTA