Protein Info for ABZR86_RS15110 in Dyella japonica UNC79MFTsu3.2

Annotation: type I restriction-modification system subunit M

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 518 transmembrane" amino acids 382 to 402 (21 residues), see Phobius details TIGR00497: type I restriction-modification system, M subunit" amino acids 6 to 501 (496 residues), 656.8 bits, see alignment E=1.2e-201 PF12161: HsdM_N" amino acids 10 to 157 (148 residues), 61 bits, see alignment E=3.1e-20 PF02384: N6_Mtase" amino acids 171 to 479 (309 residues), 396.3 bits, see alignment E=1.5e-122 PF01170: UPF0020" amino acids 202 to 304 (103 residues), 22.4 bits, see alignment E=1.3e-08

Best Hits

Swiss-Prot: 84% identical to T1MP_ECOLX: Type I restriction enzyme EcoprrI M protein (hsdM) from Escherichia coli

KEGG orthology group: K03427, type I restriction enzyme M protein [EC: 2.1.1.72] (inferred from 86% identity to plu:plu4319)

Predicted SEED Role

"Type I restriction-modification system, DNA-methyltransferase subunit M (EC 2.1.1.72)" in subsystem Restriction-Modification System (EC 2.1.1.72)

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.72

Use Curated BLAST to search for 2.1.1.72

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2GJD0 at UniProt or InterPro

Protein Sequence (518 amino acids)

>ABZR86_RS15110 type I restriction-modification system subunit M (Dyella japonica UNC79MFTsu3.2)
MTSTQQRAALQRQIWQIANDVRGAVDGWDFKQYVLGTLFYRFISENFASYIEGGDDSIQY
AKVADNVITADIKDDAIKTKGYFIYPGQLFANVVTQASNNETLNTDLARIFAAIESSASG
YPSEHDIKGLFADFDTTSNRLGNTVKEKNARLAAVLKGVAGLDFGGFDASHIDLFGDAYE
FLISNYAANAGKSGGEFFTPQHVSKLIARLAMHKQASVNKIYDPACGSGSLLLQAKKQFE
EHIIEDGFYGQEINHTTYNLARMNMFLHNINYDKFNIQLGDTLRTPHFDDEKPFDAIVSN
PPYSVKWIGSDDPTLINDDRFAPAGVLAPKSKADFAFVLHALHYLSSKGRAAIVCFPGIF
YRGGAEQKIRQYLVDNNYVETVIALAPNLFFGTTIAVNILVLSKHKTDTKTQFINASGLF
DKKTNNNELSDRYIEQIMQVFDSKAGVAHFAKSVAYEAIAGNDYNLSVSSYVEARDNREV
VDITQVNAELKTTVAKIDRLRAEIDAIVAEIESGTAEA