Protein Info for ABZR86_RS13615 in Dyella japonica UNC79MFTsu3.2

Annotation: F0F1 ATP synthase subunit alpha

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 516 TIGR00962: ATP synthase F1, alpha subunit" amino acids 6 to 513 (508 residues), 827.2 bits, see alignment E=2.6e-253 PF02874: ATP-synt_ab_N" amino acids 31 to 95 (65 residues), 39 bits, see alignment E=1.5e-13 PF00006: ATP-synt_ab" amino acids 152 to 378 (227 residues), 269 bits, see alignment E=4.4e-84 PF00306: ATP-synt_ab_C" amino acids 385 to 509 (125 residues), 143.3 bits, see alignment E=7.6e-46

Best Hits

Swiss-Prot: 83% identical to ATPA_XANC5: ATP synthase subunit alpha (atpA) from Xanthomonas campestris pv. vesicatoria (strain 85-10)

KEGG orthology group: K02111, F-type H+-transporting ATPase subunit alpha [EC: 3.6.3.14] (inferred from 83% identity to xcv:XCV3769)

MetaCyc: 78% identical to ATP synthase F1 complex subunit alpha (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"ATP synthase alpha chain (EC 3.6.3.14)" in subsystem F0F1-type ATP synthase (EC 3.6.3.14)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.14

Use Curated BLAST to search for 3.6.3.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2EKT3 at UniProt or InterPro

Protein Sequence (516 amino acids)

>ABZR86_RS13615 F0F1 ATP synthase subunit alpha (Dyella japonica UNC79MFTsu3.2)
MSSTTLNPSEISELIKTRIEQFKLGAEARNEGTIISVSDGIVRIHGLADVMQGEMIELPG
NAFALALNLERDSVGAVVLGEYQHLREGDTAKTTGRILEVPVGPELLGRVVDSLGAPIDG
KGPLNAKLSSPIEKVAPGVIWRKSVDQPVQTGYKSVDSMIPIGRGQRELIIGDRQTGKTA
LAIDAIINQKDSGIKCIYVAIGQKRSSIANVVRKLEENGALANTIVVVASASESAALQYI
APYAGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRL
LERAARVSEEYVEKFTNGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLET
DLFNAGIRPAVNAGISVSRVGGSAQTKIVKKLSGGVKLALAQFRELAAFAQFASDLDPAT
RAQLDRGQRVTELMKQKQYAPLSIAELALSVYAAEKGYLDDLAVDKVLPFEKGLHAFFHQ
NQGELMKKIVATGDWNNDIEATFKSGLDEYKKTGSW