Protein Info for ABZR86_RS13410 in Dyella japonica UNC79MFTsu3.2

Annotation: HlyD family secretion protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 337 transmembrane" amino acids 6 to 27 (22 residues), see Phobius details PF13533: Biotin_lipoyl_2" amino acids 44 to 93 (50 residues), 67.1 bits, see alignment 1.4e-22 PF16576: HlyD_D23" amino acids 128 to 269 (142 residues), 37.4 bits, see alignment E=2.6e-13 PF13437: HlyD_3" amino acids 196 to 282 (87 residues), 34.7 bits, see alignment E=3.7e-12

Best Hits

KEGG orthology group: None (inferred from 61% identity to abo:ABO_0017)

Predicted SEED Role

"Membrane fusion component of tripartite multidrug resistance system" in subsystem Multidrug Resistance, Tripartite Systems Found in Gram Negative Bacteria

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2EM81 at UniProt or InterPro

Protein Sequence (337 amino acids)

>ABZR86_RS13410 HlyD family secretion protein (Dyella japonica UNC79MFTsu3.2)
MKIPSLLRFALTAVVVVVAALLGHALWRHYMYSPWTRDGRVRAEVVRIAPDVSGLVTRVA
VIDNQQVKKGDLLFAIDKPRFEYAVAQAQANLAAAEASARAAGANINAALASAAARKADY
EMASSQAQRRQRLGDVVSQEVRADAQSSANAARATWQQAQASGSQASASRQQAEAAVEQA
QVALDRARLDLERTEVRAPVDGYVTNLDIRVGDYAATGSPRLALIDSHSYYIYGYFEETK
LPHLRVGDPVNIRLMAGGAHLKGQIIGIARGITDRDNPTGSDLLADVNPTFNWVRLAQRV
PVRIAIDTGHLPPEVLIAAGMTATIEVQPRADGRETD