Protein Info for ABZR86_RS13060 in Dyella japonica UNC79MFTsu3.2

Annotation: ATP-dependent helicase HrpB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 836 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details TIGR01970: ATP-dependent helicase HrpB" amino acids 5 to 835 (831 residues), 1049.5 bits, see alignment E=0 PF00270: DEAD" amino acids 23 to 165 (143 residues), 31.4 bits, see alignment E=3.1e-11 PF00271: Helicase_C" amino acids 208 to 329 (122 residues), 54.9 bits, see alignment E=1.9e-18 PF04408: HA2_N" amino acids 390 to 416 (27 residues), 29.3 bits, see alignment (E = 1.4e-10) PF08482: HrpB_C" amino acids 690 to 822 (133 residues), 180.3 bits, see alignment E=4.5e-57

Best Hits

KEGG orthology group: K03579, ATP-dependent helicase HrpB [EC: 3.6.4.13] (inferred from 62% identity to sml:Smlt4524)

Predicted SEED Role

"ATP-dependent helicase HrpB"

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.13

Use Curated BLAST to search for 3.6.4.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2ESI7 at UniProt or InterPro

Protein Sequence (836 amino acids)

>ABZR86_RS13060 ATP-dependent helicase HrpB (Dyella japonica UNC79MFTsu3.2)
MTFAFPITPLLPDIRASLAAHPRLVLEAPPGAGKTTQVPLALLDEAWLGGGKLLMLEPRR
IAARAAAQFMARQLGQEPGQTVGYRIRFESKVSAATRIEVVTEGILTRLIQDDPELTGIG
AILFDEFHERHLAGDLGAALALDVQATLRPELRLVVMSATLDGERIAQWLDAPRLSSPGR
SYPVRIDYPPARTQESTEHHLARVARQALEENDGDVLAFLPGRREIARAEAVLAQTLERD
DIDVVALHGELSMAEQQAALSPAEPGTRRIVLATNVAESSVTLPGIRAVVDSGLAREPRF
DPNSGFTRLETVNISQASADQRAGRAGRVAEGTAYRLWAQSRRLEPSRTAEIGQAELSGL
ALELAAWGVTADSGALPWLDAPPAGALAQARELLIALGALDASTRITPLGRRMLELGAAP
RLAAAALRAPAELHALVADLLALMEARSPLRGEQARSDDFRARVDALHAWRDRRTAGARG
GADTGALAAIEQASKGWRKRLDLRTAASGVPDSHAVGDLLLHAFPDRVARRDDNNPLRYT
LANGRGARLHESTALLGEPWLVALDLRYEARDSLILAAAPLDPRALERDYPAQFRRERAL
RWNDERNAVEAFDEHRYASIVLSRRSVPVQAEDALPALLAAIRAKGLDALPWSENARRLR
LRMQAVREWMPELGLPDVSDQALLDSLESWLAPYLDGKRRFDALSAEELSQALGSLFDYE
QRRALDTHAPENLTVPSGMSRRIEYAAGEPPVLAVKLQELFGLADTPRVGNGRVPVTLHL
LSPAGRPIQVTQDLKGFWERTYPEVKKELKGRYPRHPWPDDPWSATPTHRAKPRGT