Protein Info for ABZR86_RS12830 in Dyella japonica UNC79MFTsu3.2

Annotation: DNA primase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 578 TIGR01391: DNA primase" amino acids 4 to 414 (411 residues), 462.4 bits, see alignment E=6.6e-143 PF01807: zf-CHC2" amino acids 6 to 100 (95 residues), 132.6 bits, see alignment E=1.5e-42 PF08275: DNAG_N" amino acids 124 to 248 (125 residues), 133.7 bits, see alignment E=1.7e-42 PF13662: Toprim_4" amino acids 257 to 322 (66 residues), 60.3 bits, see alignment E=7.2e-20 PF13362: Toprim_3" amino acids 258 to 352 (95 residues), 31.1 bits, see alignment E=1.1e-10 PF01751: Toprim" amino acids 258 to 334 (77 residues), 51.7 bits, see alignment E=3.3e-17 PF13155: Toprim_2" amino acids 259 to 346 (88 residues), 59.6 bits, see alignment E=1.3e-19 PF10410: DnaB_bind" amino acids 366 to 417 (52 residues), 51.7 bits, see alignment 3.4e-17 PF08278: DnaG_DnaB_bind" amino acids 443 to 566 (124 residues), 95.4 bits, see alignment E=1.4e-30

Best Hits

KEGG orthology group: K02316, DNA primase [EC: 2.7.7.-] (inferred from 56% identity to smt:Smal_0323)

Predicted SEED Role

"DNA primase (EC 2.7.7.-)" in subsystem DNA-replication or Macromolecular synthesis operon (EC 2.7.7.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.-

Use Curated BLAST to search for 2.7.7.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2EW61 at UniProt or InterPro

Protein Sequence (578 amino acids)

>ABZR86_RS12830 DNA primase (Dyella japonica UNC79MFTsu3.2)
MRGRIPDTFIDELLSRVDIVDVIERRVPLKKAGREWTACCPFHNERSPSFYVSPAKQFFH
CFGCGAHGSAIKFLMDYDRLEFPDAVEELAQSVGLKVPYEGGRDNAPREDKTDLYALLDG
SARWYENQLPHSPEAQAYCKKRGLDADTIARFRIGWAPAGFDGVLKALGTDAKRMQLLND
AGMVASNERGNKYDRFRERLMFPILDRRGRVIAFGGRVLQSEQGPKYLNSPETALFHKGR
ELFALWQVKQANSSLARIVVVEGYMDVIAMHQAGLPIAVATLGTATTPDHTEVLFRAAPD
VVFCFDGDRAGRAAAWKALEAALPRLRDGRQAYFLFLPDGEDPDTLIRKEGKQGFEQRLK
NATPLSEYFFGELAHDVDVGSIDGRARLAERARPLIARLPDGAFRDLMAQELERRTGARA
VLQPDAAARRPAQQPVAVQRSLVRSAIALLLAQPGMADQVERPYGFLRLDKPGIELLAEL
IDLARSRPGINPVVLVEHFAERPEYSALQKLMAATVVGEPELQRVEFFDALQRMQQQATE
QRRAFLIARSREGTLDGAEKAELRELLALRVQPPATSN