Protein Info for ABZR86_RS11970 in Dyella japonica UNC79MFTsu3.2

Annotation: aminopeptidase P N-terminal domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 PF05195: AMP_N" amino acids 22 to 141 (120 residues), 117.3 bits, see alignment E=3.3e-38 PF00557: Peptidase_M24" amino acids 195 to 425 (231 residues), 207.7 bits, see alignment E=1.8e-65

Best Hits

KEGG orthology group: K01262, Xaa-Pro aminopeptidase [EC: 3.4.11.9] (inferred from 60% identity to psu:Psesu_2639)

Predicted SEED Role

"Xaa-Pro aminopeptidase (EC 3.4.11.9)" (EC 3.4.11.9)

Isozymes

Compare fitness of predicted isozymes for: 3.4.11.9

Use Curated BLAST to search for 3.4.11.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2GYT0 at UniProt or InterPro

Protein Sequence (450 amino acids)

>ABZR86_RS11970 aminopeptidase P N-terminal domain-containing protein (Dyella japonica UNC79MFTsu3.2)
MRGWPQQAQQRHRALSIAQDEYARRRRQLMKMAGEDAVLLVAAAPERIRNADAAWPYRQD
SDLHYLAGFPEPDAVLALLPGRQHGEVVLFCRERDDERERWHGESIGTERAVSEHGMDDA
FPIDDIDDILPGMIEGRARVYCHFGREPEFDARLLGWMRRLRQLRGGGVVPKEFVALGHL
LHDLRLYKSRAELRLMRSSAAIAAEAHLSAMRMALAGRHEYEVEAELVRSMRSRGAVPAF
PPIVAAGTNACVMHYTANRAPLRDGDLLLIDAGAELDCYASDISRSFPLNGRYSREQRAL
YEVVLAAQQAAIEQVRPGRPFSAAHKVAVYLIAEGLCSLGLLQGDAETAIAEGAYKRFFP
AKTGHWLGLDVHDVGDYRIDGEPRILEPGMVVTVEPGIYVPPGERSVHERWRGIGIRIED
DVAVTRDGNEVLTAAVPKEAEAIEALLAER