Protein Info for ABZR86_RS11815 in Dyella japonica UNC79MFTsu3.2

Annotation: penicillin-binding protein 1A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 835 transmembrane" amino acids 7 to 32 (26 residues), see Phobius details PF00912: Transgly" amino acids 58 to 234 (177 residues), 201.3 bits, see alignment E=1.3e-63 TIGR02074: penicillin-binding protein, 1A family" amino acids 69 to 769 (701 residues), 543.9 bits, see alignment E=2.3e-167 PF17092: PCB_OB" amino acids 321 to 429 (109 residues), 96.8 bits, see alignment E=2e-31 PF00905: Transpeptidase" amino acids 436 to 613 (178 residues), 75.4 bits, see alignment E=7.3e-25

Best Hits

Predicted SEED Role

"Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-)" in subsystem Peptidoglycan Biosynthesis or Type IV pilus (EC 2.4.1.129, EC 3.4.-.-)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.129, 3.4.-.-

Use Curated BLAST to search for 2.4.1.129 or 3.4.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2H2G3 at UniProt or InterPro

Protein Sequence (835 amino acids)

>ABZR86_RS11815 penicillin-binding protein 1A (Dyella japonica UNC79MFTsu3.2)
MQILKRLLRWVLILAFTGLLLAVAAVGVAYWLVSPRIPSVAVLKDYHMQVPLRVVTADGK
LIATFGETRRIPVAIAAVPDRLKHAVLSAEDGDFYRHPGVDWHGIARAGWHVVVSGGDKG
PGGSTITQQVARNFFLSPEKLYSRKLTEIFIALRMENELSKDQILELYLNKMFLGHRSYG
VAAAAAYYYGKSLDQLTVAECAMIASTFQLPSVVNPINNPKRGLNRRNWVLGQMLNNRYI
TQAEYQQAIAEPNDAFPHEPPIEVDAPYLAEMVRLQALDRLGNDALTEGYVIKTTVQSAR
QQSAVDALRAGLIDYDHRHGWRGPEDHQELADSAGNEDFDRILSSYTDIAGLRPGVVTGV
DGSEATVYLSSREQVKLGQDAVAWAKPYVNETRVGAPPKNVAAVLKRGDIIRLSRNAKGE
WELAQIPKVQGALASVNPEDGSLQALVGGFNFLRSKFNRAVMAARQPGSSFKPYIYSAAF
ERGFTPASIVNDAPLALPDPSRPDGLWTPSNDDDKFDGPIRLREALVKSKNLVSVRLLDA
IGVRYARDYVTRFGFSPDALPPNLSMALGTASVSPMGMARGYAVFANGGYLVTPYFISEI
DDRDGKPVYVANPARACRTCQERLLDTRPPGPPPANATVAPANSVAGTPAGAASVGGAVL
PADAHDGGHPPVLAPQVIDVRNDFLVTSLMKDVIRRGTGAAAMALGRDDLAGKTGSTNEH
RDAWFVGFNGDLSTAVWVGFDDFGSLGRGEFGAKAALPIWMDYMGAALKDRPSATLSMPP
GISTVQIDRSSGLPSEPGNPNAMPEMFKVEDVDRLRQQASQQQEDPDQQHAYDIF