Protein Info for ABZR86_RS10705 in Dyella japonica UNC79MFTsu3.2

Annotation: bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 TIGR00326: riboflavin biosynthesis protein RibD" amino acids 1 to 345 (345 residues), 380.7 bits, see alignment E=6.9e-118 PF00383: dCMP_cyt_deam_1" amino acids 1 to 93 (93 residues), 64 bits, see alignment E=1.6e-21 PF14437: MafB19-deam" amino acids 18 to 126 (109 residues), 36.3 bits, see alignment E=7e-13 TIGR00227: riboflavin-specific deaminase C-terminal domain" amino acids 140 to 347 (208 residues), 176.7 bits, see alignment E=5e-56 PF01872: RibD_C" amino acids 141 to 335 (195 residues), 163.1 bits, see alignment E=1.1e-51

Best Hits

KEGG orthology group: K11752, diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC: 1.1.1.193 3.5.4.26] (inferred from 69% identity to xal:XALc_2840)

Predicted SEED Role

"Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)" in subsystem Riboflavin, FMN and FAD metabolism (EC 1.1.1.193, EC 3.5.4.26)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.1.193 or 3.5.4.26

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2FFV4 at UniProt or InterPro

Protein Sequence (350 amino acids)

>ABZR86_RS10705 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD (Dyella japonica UNC79MFTsu3.2)
MAQALRLAERGLFTTQPNPRVGCVIAHGDEVVGEGFHPRAGEPHAEVFALRAAGERARGA
TAYVTLEPCAHHGRTPPCADALVAAGVSRVVVAAEDPFPQVAGRGLGKLRDAGIAVDIGL
MREASRALNVGFFSRIERNRPWVRVKLAMSLDGRTALANGESKWITGEAARADVQRWRAR
SSAILAGSGTVLADDPRLTARIDQPFAPPLRVVLDRQLRTPAGSHVLDGSAPTLLLHAEG
AAVPAHLQDVDRAVVPAADGGLDLAATLTLLAARGCNELHVEAGPTLCGALLAAGLADEL
LLYVAPLLLGDAARPLLQLPLLQDMGARWNLRVLDQRMLGQDLRLILRPA