Protein Info for ABZR86_RS10345 in Dyella japonica UNC79MFTsu3.2

Annotation: Hpt domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 200 400 600 800 1000 1200 1400 1600 1800 2087 transmembrane" amino acids 1909 to 1926 (18 residues), see Phobius details PF01627: Hpt" amino acids 12 to 109 (98 residues), 31 bits, see alignment 6.1e-11 amino acids 695 to 787 (93 residues), 51.3 bits, see alignment (E = 2.9e-17) amino acids 888 to 975 (88 residues), 41.8 bits, see alignment (E = 2.5e-14) amino acids 1315 to 1399 (85 residues), 46.5 bits, see alignment (E = 9.2e-16) PF02895: H-kinase_dim" amino acids 1473 to 1528 (56 residues), 23.7 bits, see alignment (E = 1.4e-08) PF02518: HATPase_c" amino acids 1661 to 1796 (136 residues), 62.2 bits, see alignment 1.5e-20 PF01584: CheW" amino acids 1801 to 1931 (131 residues), 81.2 bits, see alignment 1.4e-26 PF00072: Response_reg" amino acids 1962 to 2073 (112 residues), 96.9 bits, see alignment 2.2e-31

Best Hits

Predicted SEED Role

"Signal transduction histidine kinase CheA (EC 2.7.3.-)" in subsystem Bacterial Chemotaxis or Flagellar motility or Two-component regulatory systems in Campylobacter (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2FKC9 at UniProt or InterPro

Protein Sequence (2087 amino acids)

>ABZR86_RS10345 Hpt domain-containing protein (Dyella japonica UNC79MFTsu3.2)
MRLQDHIDFTTLQWVKPELDETLAIAREALESYVENPGDRAVMRSCADSLHQVQGTLRMV
ELYGAALVAEEMENLAVALLEGHVTQREEAYAAMMRGLMQLPDYLERLSGGHRDVPVVLL
PLLNELRASRGQQALHESALFAPNLEAALPDSAPAALNQEEAERMHGRIAELRLRFQQQL
LAWFRGQAAEQQLGAMVQTLDAIAARCYSVPGRRLWWITAGVLEGLQQGLLKNQAAEVRQ
LIGKVDRSIRQLIEQGEASMRGGDADELARKLLYVVAQSKQRSARMDLLVRTYGLDRLLP
DEGELEHARGSMSGHNRALLDSVAKAIKEDLLRVKEALDLFLRQADADPAQLSEQTGVLE
RVGDTLGMLALGVPRRVVTEQRRVLEDIANRLRAPDEELLLDVAGALLYVEASLDDHIES
LGAEEETAQEAPVSMLPRSEARHILSTLMQEATANTGKVKDAIVAFIESGWRHQELTDVP
GLMDEVSGAMRMLTAPRPAELAEGIGRFVGNELLSDRRVPTSAQMDHLADALAALEYYLE
AAREHRGGLEHILDVAEHSLSTLGYWPPPPMRTVLADAEPEAAAVPAPAPASAPAAFAPE
FTTEHELTESVSLATGHDLGSLVIGEAVTPMPSAHELAGLRLVDTEQVPAPVASGANDDD
DWVEIEEEVLEQVPVGNAINAHAGFQVSVEGIDDDIREIFLEEMQEEIDNLRDAEQKWLA
DPERLEALTPIRRSFHTLKGSGRLVGATALGEYAWKIENMLNRVLDQSIPANANAQALIH
HAIEALPQLRAALMGEGAPTAPLAAIMETADRLAGGSESARVEDFAPAATETVRRVVRRR
VLRSQIAAEAIPAATLAHVEPAPEPVAPPLHAHDMIAPPVLPPVDPVLLEILRSEVAQYL
QTIRHAINRVDGELRVDDSLLRAVHTLHGAIAMVDIPLLTQLLSPLESLLKRLRAAGHPL
SAEGVNLLGKSADAVDYIMGQFDAEHPQLPELDALIQRLVELRDAQPEPQVAHVLFEPLA
DDLAADNEADEGALAAALDAAMPAQPGEPHAEETAKAAAPVDDFTAELMAALGSFEAERP
AQDADVTHHAVAPVTAEEDDFAALYGDLTGDEPQHAEAAADPAEIVVENTLSFDNLSIEP
IELSEAHLGAGEAGHIEFSLDAVEPAEAQLVDAHALVGTEQPAEVAATHVSLEPALADGE
AAIEEIEVGPVSESELAEFLGADEPIAELAEPVSGLVDEPVLEPLHAEEAAPVVEPEHIE
TVHVETGQPEPVPFMAGEAEAAQVEEARIEPPKAPVHDLTSEYAGSWTNDQIDPDLLEIF
TEEAREILDHSDSVLAQWRAEPAEPEHLASLQRDLHTLKGGARIAGMVPVGDLTHAIETL
LESPVGRDPARLGELIRALEAGFDTLHGLVQRVSQGRGVEYPQAMIDRFLGLAGDTAPAA
GHDDVAAEPADRAGLPELLPEEGQFDEARGPQEQIRVRSELLDTLVNHAGEVAIYRSRLE
QQVAGYRFNLVELDSTVQRLRSQLRMLEIETEAQIIARFQREHREAGMSVFDPLELDRYS
QLQQYSRALAESVSDLVSIQSMLDELTRQAETLLIQQSRVSSELQDGLLRTRMLPFDTMV
PNLRRTLRQAATEQGKSAQLFVEGAHGEMDRTLLDRLKAPFEHMLRNAVAHGIESPEERR
KAGKPAEGAVRIRVAREATEVVVRVTDDGRGLDREAVRKRGIERGLLRADAKPSDDQLLA
LITQPGFSTAGTVTQLAGRGVGMDVVANEIKQLGGSIAVESQAGQGTTFVLRLPFTLAVT
QAILVRIGEGTFAIPMTSVQGVARINPADLTTRLAEYEPTFPYGGEEFGIHDLAELLGIP
PGHPGDEQLPLLLTRAGDLRAAIRIDAVIGSREIVVKSVGPQVSSVPGILGATIMGDGSV
LIILDLPPLVRHGIVRRQERLAEGLTAVEMPVVEEERVRPLVMVVDDSITMRKVTGRVLE
RHEYEVHTAKDGLDALEKLHERVPDLMLLDIEMPRMDGFELAEAMKADPRLRNVPIIMIT
SRTGDKHRQRAFDIGVDRYLGKPYQEVELLAQISEVLEQRATESAHG