Protein Info for ABZR86_RS10110 in Dyella japonica UNC79MFTsu3.2

Annotation: ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 428 transmembrane" amino acids 20 to 41 (22 residues), see Phobius details amino acids 47 to 66 (20 residues), see Phobius details amino acids 78 to 97 (20 residues), see Phobius details amino acids 102 to 119 (18 residues), see Phobius details amino acids 124 to 144 (21 residues), see Phobius details amino acids 157 to 178 (22 residues), see Phobius details PF00512: HisKA" amino acids 211 to 271 (61 residues), 34.5 bits, see alignment E=1.7e-12 PF02518: HATPase_c" amino acids 318 to 421 (104 residues), 56.1 bits, see alignment E=4.8e-19

Best Hits

KEGG orthology group: K15011, two-component system, sensor histidine kinase RegB [EC: 2.7.13.3] (inferred from 38% identity to hha:Hhal_1420)

Predicted SEED Role

"Sensor histidine kinase PrrB (RegB) (EC 2.7.3.-)" (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3, 2.7.3.-

Use Curated BLAST to search for 2.7.13.3 or 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2IKD9 at UniProt or InterPro

Protein Sequence (428 amino acids)

>ABZR86_RS10110 ATP-binding protein (Dyella japonica UNC79MFTsu3.2)
MRRSLAQQRIGPTALTRTLAWLRICAIAGQSVAVLVCALWMKLDIPLLPLLVGIGTLAVF
AVYAAWRLSQPSPLREWETILHVAADTLVLGYLLYFTGGASNPFITLLLVPIALTAATLS
VRAILAVSMLAGVAYVVLLGWYVPLPMPEHAFGPSGFTLHVAGMGVNFVISAVLLAFFTN
RLARAVRLQQVEMQRVRERALRDEGILAIATQAAGAAHELNTPLATMRTLLPELRREHAS
DTALGEDLALLEGQVERCRTILREMVAFGKAQLSQVPECTTLDGFIHGALERFQLLRPEA
DLELQMDDDAGEIVLRTPPGLRHALLNLLNNAFEASSLNQSQAVDLIAHREGDWLEFVVR
DHGPGFVPTGAPAALGQSHKLTGLGIGLALAEATAERLHGELTATNRPDGGAQMRLRLPL
AVVEARDH