Protein Info for ABZR86_RS10040 in Dyella japonica UNC79MFTsu3.2

Annotation: type IV-A pilus assembly ATPase PilB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 573 TIGR02538: type IV-A pilus assembly ATPase PilB" amino acids 15 to 573 (559 residues), 836 bits, see alignment E=7.5e-256 PF05157: MshEN" amino acids 48 to 150 (103 residues), 62.3 bits, see alignment E=4.6e-21 PF00437: T2SSE" amino acids 197 to 464 (268 residues), 361.8 bits, see alignment E=2e-112

Best Hits

Swiss-Prot: 57% identical to PILB_PSEAE: Type 4 fimbrial assembly protein PilB (pilB) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K02652, type IV pilus assembly protein PilB (inferred from 68% identity to xfn:XfasM23_2034)

Predicted SEED Role

"Type IV fimbrial assembly, ATPase PilB" in subsystem Type IV pilus

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2IKZ3 at UniProt or InterPro

Protein Sequence (573 amino acids)

>ABZR86_RS10040 type IV-A pilus assembly ATPase PilB (Dyella japonica UNC79MFTsu3.2)
MATQMQPSLAGLSGMARRLVSEGVLPEPDVRKAVLDSTQGKTSLTAWLLDHGLVDSGRLT
QLASAEFGMPAMDVSALQPANMPLNLISEALINKHHALPLFRRGKRLFVGIADPMQSHAL
DEIKFHSNCMVEPILVERAQLHRVIEGALSSMSSSVPDLGGDGLEELALEAGDDDGDSTG
IDATANDDAPVVKFVNKILVDAIKRGASDIHFEPFETNYRVRLRMDGMLRAVASPPMKLA
TRISSRLKVMAGLDIAERRVPQDGRIKLNLSKSRSVDFRVSTLPTLFGEKIVLRILDAST
AKLGIDKLGYEEVQKELYVNAIHKPYGMVLVTGPTGSGKTVSLYTALNILNTNERNISTV
EDPVEIRVEGINQVQQNTKRGMTFAAALRSFLRQDPDVIMVGEIRDLETAEIAIKAAQTG
HMVLSTLHTNDAPQTISRLMNMGIAPYNITSSVTLVIAQRLARRLHDCKKPLDLPAATLL
AAGFTQEDIDAGLTLYEAVGCDNCNEGYKGRVGIYQVMPMLEDIQKIVLQGGNAMQIAEV
SRKAGINDLRASALLKVKQGVTSLAEIDRVTKD