Protein Info for ABZR86_RS10010 in Dyella japonica UNC79MFTsu3.2

Annotation: class I SAM-dependent methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 410 PF08421: Methyltransf_13" amino acids 3 to 64 (62 residues), 81.8 bits, see alignment E=9.8e-27 PF13489: Methyltransf_23" amino acids 85 to 237 (153 residues), 56.3 bits, see alignment E=9.9e-19 PF07021: MetW" amino acids 98 to 145 (48 residues), 21.6 bits, see alignment 4.6e-08 PF08242: Methyltransf_12" amino acids 102 to 194 (93 residues), 34.1 bits, see alignment E=1.2e-11 PF08241: Methyltransf_11" amino acids 103 to 195 (93 residues), 29.5 bits, see alignment E=2.9e-10 PF08484: Methyltransf_14" amino acids 245 to 403 (159 residues), 216.5 bits, see alignment E=5.6e-68

Best Hits

Swiss-Prot: 34% identical to NOVU_STRNV: C-methyltransferase NovU (novU) from Streptomyces niveus

KEGG orthology group: None (inferred from 65% identity to slt:Slit_2896)

MetaCyc: 34% identical to dTDP-4-dehydro-beta-L-rhamnose C5-methyltransferase (Actinoalloteichus caeruleus)
2.1.1.-

Predicted SEED Role

"FIG01163484: hypothetical protein"

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2IN28 at UniProt or InterPro

Protein Sequence (410 amino acids)

>ABZR86_RS10010 class I SAM-dependent methyltransferase (Dyella japonica UNC79MFTsu3.2)
MKCRHCDASLKLTFVDLGSAPPSNAYLTEEALKASERWFPLRVLVCESCWLVQTDDYADA
RELFDATYAYFSGVSVSWLEHCRGYAEAMIDRFELDGDSHVVEVASNDGSLLQYFQARGV
RSTGIEPTASTAASARAKGIAVVEEFFGSALAKELCRAGQQADLMAANNVLAHVPDINDF
VKGFATLLKPAGVVTFEFPHLLRLVAQCQFDTIYHEHFSYLSLTAIRSVMEASGLQIFDV
EELSTHGGSLRVYGQRADTAGRAVTANVARIFAEEEQAGVTTPVFYTQFQRAAETVKNEF
LEFLLKARKQGARVAAYGAAAKGNTLLNYAGVKNDLLPFVVDRSPSKQGKYLPGSRIPVV
VEDELKRDKPDYVVILPWNIREEVMQQLAYIREWGGSFVVAVPRLEIVPA