Protein Info for ABZR86_RS09395 in Dyella japonica UNC79MFTsu3.2

Annotation: aminotransferase class III-fold pyridoxal phosphate-dependent enzyme

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00202: Aminotran_3
  • amino acids 40 to 461 (422 residues), 247.3 bits, E=1.2e-77

Best Hits

KEGG orthology group: None (inferred from 84% identity to smt:Smal_1183)

Predicted SEED Role

"Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)" in subsystem Biotin biosynthesis (EC 2.6.1.62)

MetaCyc Pathways

• biotin biosynthesis I (14/15 steps found)
• biotin biosynthesis from 8-amino-7-oxononanoate I (4/4 steps found)

KEGG Metabolic Maps

• Biotin metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.6.1.62

Use Curated BLAST to search for 2.6.1.62

Sequence Analysis Tools

See A0A1I2IBU3 at UniProt or InterPro

Protein Sequence (469 amino acids)

>ABZR86_RS09395 aminotransferase class III-fold pyridoxal phosphate-dependent enzyme (Dyella japonica UNC79MFTsu3.2)
MNAYDPNAATGVIPDAQLLADEAQYSSFGDTVHYVDPPKIFRHGQGSWMYDTAGVPFLDL
QMWYSAVNFGYGNKRLNDTLKAQIDTLPQVASQYLHQTRIELAKTIAVDAQQKFGLKGRV
HFNVGGAQAVEDSLKLVRNYKNGKSLMFAFEGGYHGRTLGASSITSSYRYRRRFGHFGER
AMFIPFPYPFRRPKGMTPEEYSDACVRQFERLFETEYNGVWDPKVNQAEYAAFYVEPIQG
TGGYVIPPKNFFKDLKKVLDKYGILMVVDEIQMGFWRTGKLWSIEHFGVTPDIIVFGKAL
TNGLNPLSGLWAREEMINPEIFPPGSTHSTFNSNPLGTSLGLEVIKMGYELDYETNVAKK
GAHFLDALKDLQKRHKEIGDVDGLGLALRAEICTDDGFTPNKALLDRMVDIGLAGDLEHN
GKKIGLVLDVGGWYKNVITFAPSLDITHEEIDLAIALLDQLLTKAKKAM