Protein Info for ABZR86_RS09355 in Dyella japonica UNC79MFTsu3.2
Annotation: sulfite reductase flavoprotein subunit alpha
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K00380, sulfite reductase (NADPH) flavoprotein alpha-component [EC: 1.8.1.2] (inferred from 56% identity to reh:H16_B2500)Predicted SEED Role
"probable oxidoreductase"
MetaCyc Pathways
- superpathway of L-methionine biosynthesis (by sulfhydrylation) (11/12 steps found)
- superpathway of sulfate assimilation and cysteine biosynthesis (8/9 steps found)
- assimilatory sulfate reduction I (4/4 steps found)
- assimilatory sulfate reduction III (3/3 steps found)
- superpathway of sulfur amino acid biosynthesis (Saccharomyces cerevisiae) (8/10 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 1.8.1.2
Use Curated BLAST to search for 1.8.1.2
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A1I2I5S3 at UniProt or InterPro
Protein Sequence (534 amino acids)
>ABZR86_RS09355 sulfite reductase flavoprotein subunit alpha (Dyella japonica UNC79MFTsu3.2) MNPAVTGGGREALGHALALLPLAALAAWLFSLQAGAMHWRDPGAERWLEASASVAAWLAL LGWLRWRRRAPADAAPLADALLVAYASQTGFAAQLAQQTVDSLCAAGTPARLAGLDTLEE AVLRKAGRVLFVVSTTGEGDAPDEAAGFERRCLARVGDLAGLRYGLLALGDSDYADYCGF GRRLRHWLAQSGAQPLFDPVEVDNGDAGALRHWQHHLGMLSGATGMPDWQRAPYASWRLA ERRLLNPGSLGGPCFHLALRPEDGVLAWEAGDIAEIEPRHAAETVTRWLAATGFDGAARV GGDTLFERLARSHLPAPADVAGLDAARLAARLQALPHREYSIASVPADGELHLLVRRMHH EDGRPGLGSGWLTQDAEEGAPIALRIRANPSFRPPAADLPLILIGNGTGLAGLRALLKAR IAAGARRHWLLFGERQPDRDFFHRDELECWLREGWLERLDLAWSREPAAPAYVQQRLREA AALLWAWVDAGAAIRVCGSLAGMAPGVEEALRDALGADRLEQMRVDGRYRRDVY