Protein Info for ABZR86_RS08790 in Dyella japonica UNC79MFTsu3.2

Annotation: TRZ/ATZ family hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 446 PF01979: Amidohydro_1" amino acids 65 to 412 (348 residues), 225.7 bits, see alignment E=1e-70 PF07969: Amidohydro_3" amino acids 114 to 412 (299 residues), 60.2 bits, see alignment E=2.7e-20

Best Hits

Swiss-Prot: 47% identical to MTAD_TERTT: 5-methylthioadenosine/S-adenosylhomocysteine deaminase (mtaD) from Teredinibacter turnerae (strain ATCC 39867 / T7901)

KEGG orthology group: None (inferred from 73% identity to psu:Psesu_1209)

Predicted SEED Role

"S-adenosylhomocysteine deaminase (EC 3.5.4.28); Methylthioadenosine deaminase" (EC 3.5.4.28)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.4.28

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2DGR8 at UniProt or InterPro

Protein Sequence (446 amino acids)

>ABZR86_RS08790 TRZ/ATZ family hydrolase (Dyella japonica UNC79MFTsu3.2)
MSPGSTVIDLLIEARWVVPVEPHAVVLENHAVAVDQGVIVALLPIAEARAAYAPRERIEL
GEHALIPGLVNTHTHNPMTLLRGLADDLPLMVWLQQHIWPVEGQVIGPEFVRDGVELAVA
EMLRGGTTCANENYFFPDVIGATYRRLGFRATVGLPVIEFPTAWAKSQDEYFERATEVHD
SFRGDALIATAFAPHAPYTVSDQSFERIRVLADQLDIPVHLHTHETAHEVEEEKRKSGLR
PFQRLQQLGLVNDRLIAVHMTQLTDGEIAACAETGVSVVHCPESNLKLASGFCPAEKLRL
AGVNVAIGTDGCASNNDLDMFGEMRTAAMLAKAVSNDAAAFDAAYALRAATLNGARAMGL
EGKIGSIERGKQADLAAVRLSDLETQPLFHVASQLVYATGRHQVTDVWIAGRRKLADRIL
VDMDVDGIRARTHAWRDRIAAIDAHG