Protein Info for ABZR86_RS08525 in Dyella japonica UNC79MFTsu3.2

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 435 transmembrane" amino acids 37 to 55 (19 residues), see Phobius details amino acids 65 to 84 (20 residues), see Phobius details amino acids 94 to 113 (20 residues), see Phobius details amino acids 119 to 141 (23 residues), see Phobius details amino acids 163 to 186 (24 residues), see Phobius details amino acids 198 to 216 (19 residues), see Phobius details amino acids 245 to 263 (19 residues), see Phobius details amino acids 282 to 302 (21 residues), see Phobius details amino acids 311 to 330 (20 residues), see Phobius details amino acids 336 to 360 (25 residues), see Phobius details amino acids 372 to 393 (22 residues), see Phobius details amino acids 405 to 423 (19 residues), see Phobius details PF00083: Sugar_tr" amino acids 28 to 225 (198 residues), 102.8 bits, see alignment E=3.4e-33 amino acids 223 to 426 (204 residues), 46.3 bits, see alignment E=4.6e-16 PF07690: MFS_1" amino acids 29 to 277 (249 residues), 66.6 bits, see alignment E=3e-22 amino acids 260 to 378 (119 residues), 43 bits, see alignment E=4.3e-15

Best Hits

Swiss-Prot: 57% identical to KGTP_ECOLI: Alpha-ketoglutarate permease (kgtP) from Escherichia coli (strain K12)

KEGG orthology group: K03761, MFS transporter, MHS family, alpha-ketoglutarate permease (inferred from 73% identity to pap:PSPA7_6332)

MetaCyc: 57% identical to alpha-ketoglutarate:H+ symporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-23

Predicted SEED Role

"Alpha-ketoglutarate permease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2DM94 at UniProt or InterPro

Protein Sequence (435 amino acids)

>ABZR86_RS08525 MFS transporter (Dyella japonica UNC79MFTsu3.2)
MNSTTAGLIARAPAMTAGQRLRSIFSGSIGNLVEWYDWYVYSAFSLYFAQVFFPASDQTT
QLLNTSGIFAVGFLMRPLGGWLLGTFADRRGRKAALLLSVFMMSLGSLIIGLSPGYAQIG
VAAPILLVLARLLQGLSIGGEYGTSATYLSEMAPRESRGFWSSIQYVTLVAGQLIALALL
VVLQHFVLSTQQLHDWGWRIPFLIGALLAVIAVIIRRNMDETASFKKARQLESPLRTLMR
HPREVLTVIGLTMGGTLAFYTFTTYMQKFLVNSAGMSKADATSISTAALFVYALLQPAFG
ALSDRIGRRPLLIGFGVLGALLTYPILSTLKEAHDWWQAFGLIMAALIIVSGYTSINAVV
KAELFPTEIRAIGVGLPYALALSVFGGTAEYVALWFKKIGHEDYFYWYVTACIACSLLVY
IGMRDTRRHSRIVED