Protein Info for ABZR86_RS08495 in Dyella japonica UNC79MFTsu3.2

Annotation: alkyl hydroperoxide reductase subunit F

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 527 TIGR03140: alkyl hydroperoxide reductase subunit F" amino acids 1 to 516 (516 residues), 800.1 bits, see alignment E=3.9e-245 PF13192: Thioredoxin_3" amino acids 124 to 190 (67 residues), 31.5 bits, see alignment E=5.4e-11 PF07992: Pyr_redox_2" amino acids 212 to 503 (292 residues), 173.4 bits, see alignment E=2.5e-54 PF12831: FAD_oxidored" amino acids 213 to 242 (30 residues), 28.9 bits, see alignment (E = 2.8e-10) PF13738: Pyr_redox_3" amino acids 258 to 486 (229 residues), 59.7 bits, see alignment E=1.1e-19 PF00070: Pyr_redox" amino acids 356 to 427 (72 residues), 49.2 bits, see alignment E=2.2e-16

Best Hits

Swiss-Prot: 77% identical to AHPF_XANCH: Alkyl hydroperoxide reductase subunit F (ahpF) from Xanthomonas campestris pv. phaseoli

KEGG orthology group: K03387, alkyl hydroperoxide reductase subunit F [EC: 1.6.4.-] (inferred from 80% identity to psu:Psesu_2386)

MetaCyc: 66% identical to alkyl hydroperoxide reductase, AhpF component (Escherichia coli K-12 substr. MG1655)
RXN-8506 [EC: 1.5.1.37]; R4-RXN [EC: 1.5.1.37, 1.11.1.26]

Predicted SEED Role

"Alkyl hydroperoxide reductase protein F (EC 1.6.4.-)" in subsystem Thioredoxin-disulfide reductase (EC 1.6.4.-)

Isozymes

Compare fitness of predicted isozymes for: 1.6.4.-

Use Curated BLAST to search for 1.11.1.26 or 1.5.1.37 or 1.6.4.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2DNG3 at UniProt or InterPro

Protein Sequence (527 amino acids)

>ABZR86_RS08495 alkyl hydroperoxide reductase subunit F (Dyella japonica UNC79MFTsu3.2)
MLDADLKTQLQAYLEKVTHPIELVASLDDSAASQELAGLLEDIASLSDKVSLSRTGHDAR
KPSFAISRVGTDVQVRFAGIPLGHEFTSLVLALLQVGGHPSKAAPELLEQVRNLEGEYRF
ETFMSLSCHSCPDTVQALNLMSVVNPNIKHVAIDGALFQDEVNERQVMAVPTVFLNGEAF
DQGRMTIEQIVARLDTGAAQRDAKKIDAKAPFDVLVVGGGPAGAAAAIYAARKGIRTGVA
AERFGGQVLDTMAIENFISVTYTEGPKLAASLEQHVHEYDVDVMNMQRAEKLVAPADPNG
LFEVKLANGATLKSKTVILSTGARWRNMNVPGENEYRNKGVTYCPHCDGPLFKGKRVAVI
GGGNSGVEAAIDLAGIVGHVTLLEFDGKLRADEVLQRKLRSLPNVRIIVNAQTTEVQGDG
QKVTALLYTDRQSGDSQRVELEGVFVQIGLLPNTEWLKGTLKLSPRGEIEVDARGETSIP
GVFAAGDVTTVPYKQIVIAMGEGAKASLSAFDHLIRMPVVEAEAVAA