Protein Info for ABZR86_RS08270 in Dyella japonica UNC79MFTsu3.2

Annotation: ribonuclease R

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 837 TIGR02063: ribonuclease R" amino acids 39 to 738 (700 residues), 853.9 bits, see alignment E=9.9e-261 PF08461: HTH_12" amino acids 42 to 97 (56 residues), 27.4 bits, see alignment 6.5e-10 TIGR00358: VacB and RNase II family 3'-5' exoribonucleases" amino acids 96 to 738 (643 residues), 707 bits, see alignment E=2.3e-216 PF08206: OB_RNB" amino acids 107 to 164 (58 residues), 71.5 bits, see alignment 9.3e-24 PF17876: CSD2" amino acids 185 to 258 (74 residues), 77 bits, see alignment E=2.4e-25 PF00773: RNB" amino acids 280 to 605 (326 residues), 364.9 bits, see alignment E=1e-112 PF00575: S1" amino acids 656 to 735 (80 residues), 48.4 bits, see alignment E=2.6e-16

Best Hits

Swiss-Prot: 48% identical to RNR_HAEIN: Ribonuclease R (rnr) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K12573, ribonuclease R [EC: 3.1.-.-] (inferred from 62% identity to xal:XALc_2000)

Predicted SEED Role

"3'-to-5' exoribonuclease RNase R" in subsystem RNA processing and degradation, bacterial

Isozymes

Compare fitness of predicted isozymes for: 3.1.-.-

Use Curated BLAST to search for 3.1.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2DS27 at UniProt or InterPro

Protein Sequence (837 amino acids)

>ABZR86_RS08270 ribonuclease R (Dyella japonica UNC79MFTsu3.2)
MPGKAAPAPRKRAASAPAARDAADPHAEREAQRYERPIPSREAILALLTERGELLSEARI
AEALQLHDEYDLHALRKRLGAMVRDGQLLLGRRGGYAPSNKLDLIAGQVLANAEGYGFLR
PDDGTEDLYLSPQQMRQVLHGDRVLASVVGLDRRGRKQGAIVEVLQRRSPRLVGRVLLEN
GVTMVAPDDRRVHQDIMIKPGQDQGARNGQIVVVEITDPPTPHRGPMGNILAVLGERLEP
SLLVEMAIASYDLPREWPAEVTREAAQVEPKVTAAEREGRVDLRALPLVTIDGADARDFD
DAVYAEPRRGGGYRLVVAIADVSHYVPVGGALDREAYERSTSTYFPGFVVPMLPETLSNG
ICSLNPKVERLCMVCDMTVDEEGEVIRSKFYSAVMYSHARCTYDRVWQAIGLNDADARHE
LADVLPQLENLHGLYQLLAAQRKRRGAIDFETPEVKFRLDNTGDVVAMGATERNDAHKLI
EECMIAANVQAAMFLEKKKIPALFRAHEQPPEEKYEDVQQFLREFKLRLPPLDEVTPGDF
ADVLRMVKDRPERELVQSVLLRAQSLAAYQPDNRGHFGLALEAYAHFTSPIRRYPDLLVH
RAIRYAVGGGKPADYVYSPAQMAAMALHCSQRERRAEEAERDVDERYKCAWMSKHVGSEF
DGTVTGVTSFGLFVELKESRVSGLVHISQLSNDYYHFDPIRHLLKGERSGAQFRLGDHVR
VQVLRASLEDRKIDFRLVGKREPFAPPPRAERAYDYAQSGERYSLPKLPKAPEQGRKPGP
SRDNARDAAPPSRFSAGGAKAKSAGGAKGKGGAPRKPGPASGKPRSDKGQGKGKGKR