Protein Info for ABZR86_RS08170 in Dyella japonica UNC79MFTsu3.2

Annotation: methionine--tRNA ligase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 699 PF09334: tRNA-synt_1g" amino acids 6 to 399 (394 residues), 487.8 bits, see alignment E=4.2e-150 TIGR00398: methionine--tRNA ligase" amino acids 6 to 541 (536 residues), 530 bits, see alignment E=7.1e-163 PF00133: tRNA-synt_1" amino acids 10 to 63 (54 residues), 33.4 bits, see alignment 4.4e-12 TIGR00399: methionine--tRNA ligase, beta subunit" amino acids 570 to 698 (129 residues), 131.4 bits, see alignment E=2e-42 PF01588: tRNA_bind" amino acids 602 to 696 (95 residues), 77.4 bits, see alignment E=1.5e-25

Best Hits

Predicted SEED Role

"Methionyl-tRNA synthetase (EC 6.1.1.10)" (EC 6.1.1.10)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.1.1.10

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2DUB0 at UniProt or InterPro

Protein Sequence (699 amino acids)

>ABZR86_RS08170 methionine--tRNA ligase (Dyella japonica UNC79MFTsu3.2)
MSRRLLVTNALPYANGPLHLGHMVGYIQADIWVRAQRMQGDEVFYVCADDAHGTPIMLAA
EKAGLAPETYIEGVQLSHESDFAAFGVAFDHYHSTHSDENRELASLIYTRLRDGGYIARR
TIQQLFDPEKTMFLPDRYIKGTCPVCGTPDQYGDNCENCGATYAPTDLIDPYSVMSGATP
VLRDSEHYFFELGKFESLLRDWFAGKLTGGAPVANSGVIAKLREWLDGGLKDWDISRDAP
YFGFPIPDAPGKFFYVWLDAPVGYLASFKALCAKTGTRFEDFLAPDSRAEMHHFIGKDII
NFHGLFWPAMLHGADFRTPTALHVNGYLTVNGAKMSKSRGTFIKARTYLDVGLHPEFLRY
YFASMLGDTPVDVDLDLKSFEERVNSHLVGKWVNIASRTAGFVQKFFDGRLAPAFGKEEA
GLWRELMTHYDEVPALYRQGEFAEVTRKFVQIADLVNGHIAAKAPWNMAKDNTRKQELHQ
VCSFAIAAFRLLAGLLKPMLPATVEKAGRFLDAPVTGFDDARAELHNHTIHAFEPLLGRI
DTKLIEAMVEASRDSLAPPEPAKPAKLHKNESKKDNGKTMSDTGSTDTAATIAIDDFARL
DLRIGKVTACEFVDGSDKLLRFELDAGPLGTRQIFSGIRAAYGEPEKLVGRNVVFIANLA
PRKMRFGLSEGMILSAGDGGDDLFLLDADQGAKPGATVR