Protein Info for ABZR86_RS07870 in Dyella japonica UNC79MFTsu3.2

Annotation: imidazolonepropionase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 410 TIGR01224: imidazolonepropionase" amino acids 27 to 404 (378 residues), 469.8 bits, see alignment E=2.8e-145 PF01979: Amidohydro_1" amino acids 66 to 405 (340 residues), 81.8 bits, see alignment E=5.8e-27 PF07969: Amidohydro_3" amino acids 118 to 405 (288 residues), 62.9 bits, see alignment E=4.2e-21

Best Hits

Swiss-Prot: 62% identical to HUTI_RHORT: Imidazolonepropionase (hutI) from Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)

KEGG orthology group: K01468, imidazolonepropionase [EC: 3.5.2.7] (inferred from 68% identity to psu:Psesu_2247)

MetaCyc: 62% identical to imidazolonepropionase (Pseudomonas fluorescens)
Imidazolonepropionase. [EC: 3.5.2.7]

Predicted SEED Role

"Imidazolonepropionase (EC 3.5.2.7)" in subsystem Histidine Degradation (EC 3.5.2.7)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.2.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2DZF9 at UniProt or InterPro

Protein Sequence (410 amino acids)

>ABZR86_RS07870 imidazolonepropionase (Dyella japonica UNC79MFTsu3.2)
MNTASWDLLLTGATLATFDGGQPYGLIEDGALAMAGGRIAWIGPRAQLPADAQARAASVE
HLDGALVTPGLVDCHTHLVFGGDRAHEFDLRLNGASYEEIARAGGGIASTVKATREADED
ELFTQALPRARALLADGVTTLEIKSGYGLELESERRMLRVARRLGEALGIGVRTSFLGLH
ALPAEYREDRDGYVALVCDRILPALAAEGLVDAVDAFCEGIGFTREETRRVFERARSLGL
PVKLHAEQLSNLEGAALVAEYDGLSADHLEYLSEDGVRAMAAKGTVAVLLPGAFYALRET
KLPPIAALREHGVAMAVATDCNPGTSPLLSLRLAAGMACTLFRLTPEEALRGVTVHAARA
LGLDDRGTLAVGQRADLVVWQVQRPAELCYWIGGGLVRAVYCGGRRIETA