Protein Info for ABZR86_RS07855 in Dyella japonica UNC79MFTsu3.2

Annotation: formimidoylglutamate deiminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR02022: formiminoglutamate deiminase
  • amino acids 6 to 451 (446 residues), 597.8 bits, E=6.5e-184
• PF01979: Amidohydro_1
  • amino acids 46 to 427 (382 residues), 113.7 bits, E=5.9e-37

Best Hits

KEGG orthology group: K05603, formimidoylglutamate deiminase [EC: 3.5.3.13] (inferred from 58% identity to rce:RC1_3235)

Predicted SEED Role

"Formiminoglutamic iminohydrolase (EC 3.5.3.13)" in subsystem Histidine Degradation (EC 3.5.3.13)

MetaCyc Pathways

• L-histidine degradation II (5/5 steps found)

KEGG Metabolic Maps

• Histidine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.3.13

Sequence Analysis Tools

See A0A1I2DZA9 at UniProt or InterPro

Protein Sequence (453 amino acids)

>ABZR86_RS07855 formimidoylglutamate deiminase (Dyella japonica UNC79MFTsu3.2)
MSDATRTYSADQLWLADGWSADGAFAVDASGHVAPPEGEAERLGAWVLPGMPNLHSHAFQ
RAMAGLAERKGRSDDSFWTWRETMYAFAAAIGPEELKAIAAQLYVEMLKAGYTQVCEFHY
LHHQPDGTPYAQPEAMSLALIEAARETGITLTLLPVLYMTGGFDGRPLSARQRRFGNDLS
SYVRLLEALRRHEGDGLRIGIALHSLRAVPEEAMRGLLATRIAQDLPVHIHIAEQIGEVQ
DCLATRGARPVEWLLDHAPVDARWTLVHATHLTGHETSRLARSGAVAGLCPTTEANLGDG
LFPLSDYLDAKGVLGIGSDSHISISPVEELRWLEYGQRLSTRHRNIAARREGDSVGETLW
RAALRGGARAAGLPVGELRAAARADLLVLDDESPLLAARDARSLLDSFLFAGNTPLVRHV
MCGGRWVVRDFRHHDEAGIAARYRAVVERLAQA