Protein Info for ABZR86_RS07615 in Dyella japonica UNC79MFTsu3.2

Annotation: cytochrome o ubiquinol oxidase subunit III

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00510: COX3
  • amino acids 28 to 208 (181 residues), 57.4 bits, E=1.1e-19
• TIGR02842: cytochrome o ubiquinol oxidase, subunit III
  • amino acids 31 to 210 (180 residues), 272.8 bits, E=9.1e-86

Best Hits

Swiss-Prot: 61% identical to CYOC_PSEPU: Cytochrome bo(3) ubiquinol oxidase subunit 3 (cyoC) from Pseudomonas putida

KEGG orthology group: K02299, cytochrome o ubiquinol oxidase subunit III [EC: 1.10.3.-] (inferred from 80% identity to mpt:Mpe_A1742)

MetaCyc: 60% identical to cytochrome bo terminal oxidase subunit III (Pseudomonas putida KT2440)
RXN0-5268 [EC: 7.1.1.3]

Predicted SEED Role

"Cytochrome O ubiquinol oxidase subunit III (EC 1.10.3.-)" in subsystem Terminal cytochrome O ubiquinol oxidase or Terminal cytochrome oxidases (EC 1.10.3.-)

MetaCyc Pathways

• D-lactate to cytochrome bo oxidase electron transfer (2/2 steps found)
• NADH to cytochrome bo oxidase electron transfer I (2/2 steps found)
• glycerol-3-phosphate to cytochrome bo oxidase electron transfer (2/2 steps found)
• pyruvate to cytochrome bo oxidase electron transfer (2/2 steps found)
• succinate to cytochrome bo oxidase electron transfer (2/2 steps found)
• NADH to cytochrome bo oxidase electron transfer II (1/2 steps found)
• proline to cytochrome bo oxidase electron transfer (1/2 steps found)

Isozymes

Compare fitness of predicted isozymes for: 1.10.3.-

Use Curated BLAST to search for 1.10.3.- or 7.1.1.3

Sequence Analysis Tools

See A0A1I2FV18 at UniProt or InterPro

Protein Sequence (211 amino acids)

>ABZR86_RS07615 cytochrome o ubiquinol oxidase subunit III (Dyella japonica UNC79MFTsu3.2)
MSDAKSYDTYNTAAAPLRFHQETEHHPENGTLLGFWLYLMSDCLIFACLFAVYGVLGRSY
AGGPTGAEIFELPLVALNTSLLLLSSITYGFAMLEMQRNRVNGTLVWLAVTGLLGAGFIG
IELYEFGNLIAEGNGPQRSAFLSSFFTLVGTHGLHVSCGIIWLITLMVQVKRKGLIGPNK
RRLWCLSMFWHFLDVVWIGVFSFVYLMGVLP