Protein Info for ABZR86_RS07565 in Dyella japonica UNC79MFTsu3.2

Annotation: efflux RND transporter periplasmic adaptor subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 403 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details TIGR01730: efflux transporter, RND family, MFP subunit" amino acids 38 to 376 (339 residues), 262.8 bits, see alignment E=1.9e-82 PF16576: HlyD_D23" amino acids 61 to 297 (237 residues), 57 bits, see alignment E=2.6e-19 PF13533: Biotin_lipoyl_2" amino acids 64 to 110 (47 residues), 35.8 bits, see alignment 8.2e-13 PF13437: HlyD_3" amino acids 173 to 294 (122 residues), 31.4 bits, see alignment E=4e-11

Best Hits

Swiss-Prot: 42% identical to TTGA_PSEPK: Probable efflux pump periplasmic linker TtgA (ttgA) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)

KEGG orthology group: K03585, membrane fusion protein (inferred from 58% identity to sml:Smlt3170)

Predicted SEED Role

"RND efflux system, membrane fusion protein CmeA" in subsystem Multidrug Resistance Efflux Pumps or Multidrug efflux pump in Campylobacter jejuni (CmeABC operon)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2FV90 at UniProt or InterPro

Protein Sequence (403 amino acids)

>ABZR86_RS07565 efflux RND transporter periplasmic adaptor subunit (Dyella japonica UNC79MFTsu3.2)
MKSSSLRTPLLCLGLLALAACGGKKEQGPPQMPTPEVGVVKAQPVSAPLNKDLVGRLSAF
RSADVRARVSGVLLKRVYEEGTDVKKGQVLFEIDPSIYQANLNSAQANLASAQATYANAH
KAAERARQLRPQGYVSQSDLDSAEASERSSAAAVKQSQAAVESSRISLGFTRVTAPIDGR
AGQQQVTEGAIVGNGNADAGASSTLLTTVDQLDPLYINFTVGAGDLDRLRRAQSAGHVSL
NDPTKTTVQVVLPDGSTYDQQGTLDFSGATVDPTTGTVNLRAQLANPDKRLLPGTYVTVK
ANLGQQNNVFLVPQQGVARDVAGAYVLVVNQEGKVQRKDITANDLSNGNWIVTGGLAAGD
QVIVSGLQSVQPGAPAKASPWQPGKDAGPPNGAPGGQPAAGKH