Protein Info for ABZR86_RS07560 in Dyella japonica UNC79MFTsu3.2
Annotation: NAD-glutamate dehydrogenase domain-containing protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Predicted SEED Role
"NAD-specific glutamate dehydrogenase (EC 1.4.1.2), large form" in subsystem Glutamate dehydrogenases or Glutamine, Glutamate, Aspartate and Asparagine Biosynthesis (EC 1.4.1.2)
MetaCyc Pathways
- L-alanine degradation II (to D-lactate) (3/3 steps found)
- L-glutamate degradation I (1/1 steps found)
- ethene biosynthesis IV (engineered) (1/3 steps found)
- L-glutamate degradation V (via hydroxyglutarate) (5/10 steps found)
- methylaspartate cycle (11/19 steps found)
- L-glutamate degradation XI (reductive Stickland reaction) (2/7 steps found)
- 4-aminobutanoate degradation V (1/7 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 1.4.1.2
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A1I2FUH4 at UniProt or InterPro
Protein Sequence (1644 amino acids)
>ABZR86_RS07560 NAD-glutamate dehydrogenase domain-containing protein (Dyella japonica UNC79MFTsu3.2) MNAIRAASETSIQAEVLDELKKSGFPTQRLDEAQFFISAFFSRVAAGDLELHTASEWAGL IAGLLDFVQQRQPGRAAVRVFNPQAGHAGRSVVQIATDDMPFLVDTVSMIVSTRLQIHAV IHPVVKAVRDASGRLQRLGADDGAPESVMHFEIDRLADEAEMAQLKTQIESSLDDVRASV NDWSRMRDQALAIAADLPNRQLPLNKDSMQEAVEFMRWLADDNFTFLGYREYEVTQADGD EVLRSLEGSGLGILHKQERSMAPRSLRSMAASELPQSGSTDAIILTKTNARSHVHRQGHM DYVGVLRFDAHGKPVAEQRFLGLFSSNAYMARPQDVPLVRQRVEAVMARSGLKRDSYSGK SLRHILETLPRDELFQSNEDELYATAIGILELRQRARTRLFVRRDRYGRFFTCLVFVPRE RFNTSVRERIENMLRDALHGEQIDSSVLMGEAALARLHIVVRPRIGDHVSYDAAALEQSV AAIVRNWHDDLRDALVKLMGDHDGVVLANRYGKALPAGYVEDVLPAAAAEDVRQLALLRG DDAVRMSFYHPEQRPEELRFKVYRSGADIALSEVLPQLENLGLRVLTEHVYDVKTGGTPL FIQDFEVQPVGNLTFSVEQVGSLFEDAFEQIWRVNAENDGFNRLVLGAKLSWRQVAMLRG YCKYLLQTGVAFSQNYMEDAFNRYPAIAGLLVELFLAKFDPRREELGAVELKNARAALAG EMQALIPESVRQAHPALIDGLVAALEQPRAEQIKAIEEAIGVLLENVSSLDDDRILRSFV ALIRGTLRTSFFQQWEGAYRGYISFKFDSHRVPDLPKPVPYREIFVSAPRVEGIHLRFGA VARGGLRWSDRREDFRTEVLGLVKAQMVKNTVIVPVGSKGGFVVKRPPLGGDRDAQLAEG IACYRMFINGLLDITDNLVEGKVVPPHDVVRHDADDPYLVVAADKGTATFSDIANAISLE HGFWLGDAFASGGSNGYDHKGMGITAKGAWESVKRHFRALGRDSQTQDFTCVGIGDMSGD VFGNGMLLSRHIRLLAAFDHRHIFLDPNPDAERSFVERERMFKLPRSSWDDYDKSLISAG GGVYPRTLKAIPVSPEVRAALGIKGDATQMAPNELLNAILKAPVDLLWNGGIGTYVKAAS ESHADAGDRANNALRANGAELRCKMVGEGGNLGFTQKGRIEAAQHGVLLNTDFIDNSAGV DTSDHEVNIKILLDDAVQRGELDTDARNRQLAAMTDEVGQLVLWDNYRQNQAITLMERQS VRRLGSMAHFIRILEGEGLLDRQVENLPSETELTERKTRGQGMTRPELSVLLSYDKIKLY QQLLDSDVPEDPYLSKELVRYFPEPLHEKYAEHMQRHRLKREIIATAVTNSTINRMGATF MMRMQEDTGHGPAAIAKAYTAAREILGARELWAEIEALDSKVAEETQLDAIMQIWSLLRH LTRWLLSRPGGTLEIAANVDRYQAGVAALYEAVPDTLTPTGKADFSTSQEKWEGLGLPTE LSVRMARIPELRAMLDMLEVAQQSGQPVDQVAGVFYELGEALDLEWLRSQIEALPVEGHW HAQARGSLLDELNHQHRALALQVLALAGGSKGTSPVQAWLQRDDATLKYTRNMLAEILTQ NADYPIASVAVRRLAQLAAVPVNA