Protein Info for ABZR86_RS07490 in Dyella japonica UNC79MFTsu3.2

Annotation: polyphosphate kinase 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 721 TIGR03705: polyphosphate kinase 1" amino acids 38 to 710 (673 residues), 936.4 bits, see alignment E=5.2e-286 PF13089: PP_kinase_N" amino acids 38 to 144 (107 residues), 120.8 bits, see alignment E=7.8e-39 PF02503: PP_kinase" amino acids 152 to 335 (184 residues), 211.7 bits, see alignment E=1.9e-66 PF17941: PP_kinase_C_1" amino acids 363 to 526 (164 residues), 236.9 bits, see alignment E=2.4e-74 PF13091: PLDc_2" amino acids 410 to 522 (113 residues), 31.2 bits, see alignment E=4.3e-11 PF13090: PP_kinase_C" amino acids 534 to 705 (172 residues), 220.9 bits, see alignment E=1.9e-69

Best Hits

Swiss-Prot: 75% identical to PPK1_PSEAI: Polyphosphate kinase (ppk) from Pseudomonas aeruginosa

KEGG orthology group: K00937, polyphosphate kinase [EC: 2.7.4.1] (inferred from 75% identity to pag:PLES_56361)

Predicted SEED Role

"Polyphosphate kinase (EC 2.7.4.1)" in subsystem High affinity phosphate transporter and control of PHO regulon or Phosphate metabolism or Purine conversions (EC 2.7.4.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.4.1

Use Curated BLAST to search for 2.7.4.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2FW76 at UniProt or InterPro

Protein Sequence (721 amino acids)

>ABZR86_RS07490 polyphosphate kinase 1 (Dyella japonica UNC79MFTsu3.2)
MSSSENRPSVTVEETPAAAAPAAEIQGGTQDLNDSSLYIHRELSQLQFNIRVLDQALDER
KPILERLKFLLIFSSNLDEFFEIRVAGLKSQIAFDHEIVGPDAIAPRRALTEISEIAHKQ
IERQYTILNEHVLPELSRHGIRIVRRNEWSHKQKLWVRRYFRHEVAPLVTPIGLDPTHPF
PLLVNKSLNFIVQLEGVDAFGRDSGLAVVPAPRVLPRLIRLPDEVCEGGENFVLLSSIIH
AHTEELFPGMSVRGCYQFRLTRNADLTIDPEDVEDLARALRGELYSRRFGDAVRLEVADN
CPKELTDYLLKQFGLTAAEMYEVNGPVNLTRLMGLANKSHAPQLLYPPFTPAIPKALKKE
EDLFQVVGKQDVLLLHPFESFMPVVDLLHQAAKDPNVLAIKQTLYRSGANSEIVDALVDA
ARAGKEVTVVVELRARFDEESNLTLASRLQQAGAMVIYGVVGVKTHAKLMLIQRREGDEL
VRYAHLGTGNYHTGNARLYTDYSLLTSDQALCEDVHKLFSQLTGMGKVLRMKKLLHAPFT
LKKTLLELIARETAHAQAGRAAQIIAKVNALTDPKVIRALYKASMAGVKIDLIVRGMCCL
RPGVPGVSHNIRVRSIVDRFLEHSRAYWFANNGDEELFLASADLMERNLDRRVETGFPIE
SKKLQQRVKKELELYLADNSSASLLHADGHYHRLSPGGQTVRNAQAQLLERICGVGANPV
E