Protein Info for ABZR86_RS07470 in Dyella japonica UNC79MFTsu3.2

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 418 transmembrane" amino acids 30 to 55 (26 residues), see Phobius details amino acids 62 to 81 (20 residues), see Phobius details amino acids 93 to 112 (20 residues), see Phobius details amino acids 118 to 136 (19 residues), see Phobius details amino acids 157 to 178 (22 residues), see Phobius details amino acids 184 to 206 (23 residues), see Phobius details amino acids 228 to 250 (23 residues), see Phobius details amino acids 271 to 292 (22 residues), see Phobius details amino acids 299 to 316 (18 residues), see Phobius details amino acids 322 to 344 (23 residues), see Phobius details amino acids 355 to 374 (20 residues), see Phobius details amino acids 386 to 406 (21 residues), see Phobius details PF07690: MFS_1" amino acids 36 to 267 (232 residues), 90.2 bits, see alignment E=6.6e-30 amino acids 239 to 410 (172 residues), 51.1 bits, see alignment E=5.1e-18

Best Hits

Swiss-Prot: 72% identical to FSR_ECOLI: Fosmidomycin resistance protein (fsr) from Escherichia coli (strain K12)

KEGG orthology group: K08223, MFS transporter, FSR family, fosmidomycin resistance protein (inferred from 70% identity to bmj:BMULJ_01370)

MetaCyc: 72% identical to fosmidomycin efflux pump (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-41

Predicted SEED Role

"Fosmidomycin resistance protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2FW16 at UniProt or InterPro

Protein Sequence (418 amino acids)

>ABZR86_RS07470 MFS transporter (Dyella japonica UNC79MFTsu3.2)
MQTRVEDLPLPAAQTQTQTHAKAEPRTDFGIIGAISFAHLLNDMIQSLILAIYPILKEGF
HLSFAQVGLITLTYQVTASLLQPMVGMITDRKPMPFSLPVGMGFTLCGLLLLANAPNFAL
LLVAAALVGTGSSVFHPESSRVARMASGGRHGLAQSLFQVGGNTGASLGPLLAAWIIVPH
GRGSVAWFALAALLAIVVLLQVSAWYRDHHAVRGKAKARHAAVTLTRGRVIGAVAILGLL
IFSKYFYIASITSYYTFYLIHKFGVSVQNAQTHLFVFLFAVAAGSLIGGPVGDRIGRKWV
IWASILGVAPFTLLLPHANLLWTGVLTVVIGLILSSAFSAILVYAQELIPGRVGMISGLF
FGFAFGMGGIGAAVLGKVADAQGIDFVYGICAYLPLLGVITVLLPNLDGPKRLAAKES